Circular dichroism (CD) spectroscopy measures differences in the absorption of left-handed polarized light versus right-handed polarized light that arise due to structural asymmetry. The absence of regular structure results in zero CD intensity, while an ordered structure results in a spectrum which can contain both positive and negative signals. [Product Link]
Differential scanning calorimeter for study of samples in solution. It measures intramolecular stability of proteins, nucleic acids, oligomeric proteins, nucleic acid duplexes, lipid and detergent micellar system. [Product Link]
Hybrid triple quadrupole linear ion trap mass spectrometer for drug discovery and development, metabolite identification, contaminant testing, proteomic applications, post translationally modified proteins discovery, protein identification, and biomarker validation. [Product Link]
Core provides instrumentation, training and support for any type of experimental work involving biophysical and spectroscopic measurements. The services that our core provides can be extended to partially purified proteins, whole cell assays and analysis of tissues. Equipment includes triple-quadrupole LC-MS/MS, ICP-MS for elemental analysis, circular dichroism, biolayer interference, stopped flow, Isothermal calorimeter, differential scanning calorimeter, steady-state fluorescence and polarization of fluorescence.
