University of Pittsburgh
James Conway
3501 Fifth Avenue
Pittsburgh, PA 15213
https://www.structbio.pitt.edu/index.php/facilities/cryoem
RRID: RRID:SCR_025216
1.) Wang P, Zhang X, Guseinov AA, Jenkins L, von Hallerstein C, Colburn JD, Ives R, Luscombe VB, Marsango S, Oktavia L, Raja A, Greaves DR, Biggin PC, Milligan G, Zhang C, Tikhonova IG, Russell AJ (2025 Aug 2). Steric control of signaling bias in the immunometabolic receptor GPR84 bioRxiv, (), 2025.07.30.667614. . PMCID: 12324463.
2.) Fischer HL, Kline C, Duprex WP, McCarthy KR, Watkins SC, Conway JF, Ambrose Z (2025 May 23). Deletion of the Envelope gene attenuates SARS-CoV-2 infection by altered Spike localization and increased cell-to-cell transmission bioRxiv, (), 2025.05.20.655126. . PMCID: 12140015.
3.) Huang H, Mu Y, Huang Y, Ji B, Wang Y, Chen CY, Chen Y, Luo Z, Li S, Zhang Z, Wang L, Conway JF, Yang D, Wang J, Sun J, Li S (2025 May 5). Rational development of gemcitabine-based nanoplatform for targeting SERPINB9/Granzyme B axis to overcome chemo-immune-resistance Nature Communications, 16(), 4176. . PMCID: 12053578.
4.) Blauwkamp J, Rajaram K, Staggers SR, Harrigan O, Doud EH, Prigge ST, Sun SY, Absalon S (2025 May 5). An Essential Adaptor for Apicoplast Fission and Inheritance in Malaria Parasites Research Square, (), rs.3.rs-6457426. . PMCID: 12083691.
5.) Wieteska Ł, Taylor AB, Punch E, Coleman JA, Conway IO, Lin YF, Byeon CH, Hinck CS, Krzysiak T, Ishima R, López-Casillas F, Cherepanov P, Bernard DJ, Hill CS, Hinck AP (2025 Feb 26). Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling Nature Communications, 16(), 1778. . PMCID: 11865472.
6.) Vetturini AJ, Cagan J, Taylor RE (2024 Dec 31). Generative design-enabled exploration of wireframe DNA origami nanostructures Nucleic Acids Research, 53(2), gkae1268. . PMCID: 11754647.
The Cryo-electron Microscopy Facility provides access to cutting edge instrumentation for high resolution structural analysis of proteins, protein complexes, viruses, macromolecular assemblies, cellular organelles, and bacterial cells.
