University of Pittsburgh

Contact Info:

James Conway

3501 Fifth Avenue

Pittsburgh, PA 15213

https://www.structbio.pitt.edu/index.php/facilities/cryoem

Grants and Identifiers:

RRID: RRID:SCR_025216

Instrumentation:

Services Provided:

Relevant Publications:

1.) Huang H, Mu Y, Huang Y, Ji B, Wang Y, Chen CY, Chen Y, Luo Z, Li S, Zhang Z, Wang L, Conway JF, Yang D, Wang J, Sun J, Li S (2025 May 5). Rational development of gemcitabine-based nanoplatform for targeting SERPINB9/Granzyme B axis to overcome chemo-immune-resistance Nature Communications, 16(), 4176. . PMCID: 12053578.

2.) Wieteska Ł, Taylor AB, Punch E, Coleman JA, Conway IO, Lin YF, Byeon CH, Hinck CS, Krzysiak T, Ishima R, López-Casillas F, Cherepanov P, Bernard DJ, Hill CS, Hinck AP (2025 Feb 26). Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling Nature Communications, 16(), 1778. . PMCID: 11865472.

3.) Vetturini AJ, Cagan J, Taylor RE (2024 Dec 31). Generative design-enabled exploration of wireframe DNA origami nanostructures Nucleic Acids Research, 53(2), gkae1268. . PMCID: 11754647.

Description:

The Cryo-electron Microscopy Facility provides access to cutting edge instrumentation for high resolution structural analysis of proteins, protein complexes, viruses, macromolecular assemblies, cellular organelles, and bacterial cells.