University of Pittsburgh

Contact Info:

Heidi Monroe

3500 Terrace Street

/room S765 BST

Pittsburgh, PA 15261

https://singlecell.pitt.edu/

Grants and Identifiers:

RRID: RRID:SCR_025110

Instrumentation:

Services Provided:

10x Genomics

Genomics

Single Nucleus Dissociation & Sequencing (FFPE Or Frozen)

Single-Cell Analysis

Single-cell Sequencing

Relevant Publications:

1.) Yun H, Moghbeli K, Gerges PH, Cisney RN, Yoshida M, Hawse WF, MacDonald WA, Bhuiyan SA, Renthal W, Sullivan CJ, Das J, Kaplan DH, Singh H, Davis BM, St Leger AJ (2026 Jan 27). The production of the chemokine CCL2 by corneal sensory neurons initiates anti-viral immunity at the cornea and trigeminal ganglion. Cell reports, 45(1), 116693. doi: 10.1016/j.celrep.2025.116693. PMID: 41405994.

2.) Tung TH, Babu S, Tang X, Sciutto A, Romer M, Racha P, Fisler V, Saha A, Saito T, Saido TC, Grinspan JB, Mathys H, Kozai TD, Cambi F (2025 Nov 26). Fus depleted oligodendrocytes reduce neuronal damage and attenuate AD progression in the AppNL-G-F mouse bioRxiv, (), 2025.11.24.689041. . PMCID: 12697352.

3.) Chang AC, Balic M, Bartholow T, Bhargava R, Brown DD, Brown L, Brufsky A, Cao Y, Carleton N, Clark AM, Cody M, Ding K, Deible C, Elangovan A, Foldi J, Geisler D, Hodgdon C, Howard N, Li Z, Liu JB, Lopez-Nunez O, Mary DJ, McGinn O, Miller L, Mori K, Pecar G, Priedigkeit N, Puhalla S, Rosenzweig MQ, Roy P, Savariau L, Walker S, Waltermire H, Wedn AM, Wells A, Yates ME, Xavier J, Lee AV, Oesterreich S (2025 Jun 19). Hope for OTHERS (Our Tissue Helping Enhance Research & Science): research results from the University of Pittsburgh rapid autopsy program for breast cancer Breast Cancer Research : BCR, 27(), 111. . PMCID: 12180227.

4.) Forman-Rubinsky R, Feng W, Schlegel BT, Paul A, Zuppo D, Kedziora K, Stoltz D, Watkins S, Rajasundaram D, Li G, Tsang M (2024 Dec 9). Cited4a limits cardiomyocyte dedifferentiation and proliferation during zebrafish heart regeneration. bioRxiv : the preprint server for biology, (), . . PMID: 39713454.

5.) Chang AC, Balic M, Bartholow T, Bhargava R, Brown DD, Brown L, Brufsky A, Cao Y, Carleton N, Clark AM, Cody M, Ding K, Deible C, Elangovan A, Foldi J, Geisler D, Hodgdon C, Howard N, Li Z, Liu JB, Lopez-Nunez O, Mary SJ, McGinn O, Miller L, Mori K, Pecar G, Priedigkeit N, Puhalla S, Rosenzweig MQ, Roy P, Savariau L, Walker S, Waltermire H, Wedn AM, Wells A, Yates ME, Xavier J, Lee AV, Oesterreich S (2024 Nov 8). Hope for Others: Research Results from the University of Pittsburgh Rapid Autopsy Program for Breast Cancer bioRxiv, (), 2024.11.06.621982. . PMCID: 11580927.

Description:

The Single Cell Core offers single cell sequencing to the University of Pittsburgh and surrounding communities. Our services include single cell gene expression, immune profiling, ATAC, and multiome analysis.