The Ohio State University
Jeffrey Tonniges
460 W. 12th Ave.
Biomedical Research Tower 2nd floor
Columbus, OH 43210
https://cmif.osu.edu/
RRID: RRID:SCR_025078
3D & 4D Image Processing Stations
Analysis Workstations
Brightfield Microscopy
Cell Imaging
Confocal Microscopy
Confocal/ Super Resolution Microscope
Consultation
Consultations
Correlative Light Electron Microscopy
Cryo-Ultra Microtomy
Deconvolution
Differential Interference Contrast Microscopy
Electron Microscopy
Experimental Design
Fluorescence Microscope With Optical Sectioning Capability
Immuno Electron Microscopy
Live Cell Imaging
Microscopy
Microtomy/Electron
Microtomy/Light
Multiphoton Microscopy
Multiphoton/ Harmonic Generation Microscope
Phase Contrast Microscopy
Sample Preparation
Sputter Coating
Super-resolution Microscopy
TIRF Microscopy
Tissue Embed
Tissue Processing
Training
Transmission Electron Microscopy
Widefield Microscopy
1.) Akkaya-Colak KB, Keller AR, Festing MH, Gupta K, Sledziona J, Adeniyi A, West O, Stevens P, Pietrzak M, Knoblaugh SE, Walesewicz H, Baldwin DA, Simcox JA, Ntambi J, Clinton SK, Mihaylova MM (2025 Sep 20). Stearoyl-CoA Desaturases regulate stem and progenitor cell metabolism and function in response to nutrient abundance bioRxiv, (), 2025.09.17.676943. . PMCID: 12458109.
2.) Martin CJ, Oser EA, Nagarajan P, Popova LV, Sunkel BD, Stanton BZ, Parthun MR (2025 Sep). Distinct classes of lamina-associated domains are defined by differential patterns of repressive histone methylation Genome Research, 35(9), 1959-1974. . PMCID: 12400951.
3.) Bonin K, Wang Y, Riveros I, Chen RW, Zhang B, Bundschuh R, Castro CE, Poirier MG (2025 Aug 13). Free energy spectroscopy reveals the mechanistic landscape of chromatin compaction bioRxiv, (), 2025.08.13.670082. . PMCID: 12431002.
4.) Saroj N, Dholaniya PS, Alvi SB, Sridharan D, Soni N, Ashraf SA, Choudhry A, Ashraf YA, Mikula SK, Singla DK, Khan M (2025 Jun 15). SiRNA-mediated knockdown of TOP2B protects hiPSC-derived cardiomyocytes from doxorubicin-induced toxicity. Life sciences, 371(), 123595. doi: 10.1016/j.lfs.2025.123595. PMID: 40158615.
5.) Sehgal M, Filho DA, Kastellakis G, Kim S, Lee J, Shen Y, Huang S, Lavi A, Fernandes G, Davila Mejia I, Martin SS, Pekcan A, Wu MS, Heo WD, Poirazi P, Trachtenberg JT, Silva AJ (2025 Mar). Compartmentalized dendritic plasticity in the mouse retrosplenial cortex links contextual memories formed close in time. Nature neuroscience, 28(3), 602-615. . PMID: 39962274.
6.) Bhullar AS, Jin K, Shi H, Jones A, Hironaka D, Xiong G, Xu R, Guo P, Binzel DW, Shu D (2024 Dec 4). Engineered extracellular vesicles for combinatorial TNBC therapy: SR-SIM-guided design achieves substantial drug dosage reduction. Molecular therapy : the journal of the American Society of Gene Therapy, 32(12), 4467-4481. . PMID: 39369270.
7.) Fisher M, Duhon BH, Nguyen HT, Tonniges JR, Wu KC, Ren Y (2024 Nov 7). Quantitative Assessment of Collagen Architecture to Determine Role of Tumor Stroma During Vestibular Schwannoma Progression Otolaryngology--Head and Neck Surgery, 172(2), 614-622. . PMCID: 11773437.
CMIF is a full-service facility, offering services from sample preparation to image processing. We offer a wide variety of instrumentation for use such as electron microscopy, light microscopy, and access to other instrumentation for use in sample prep.
