University of South Carolina at Columbia
Austin Worden
6311 Garners Ferry Rd
Building 1, Room B60
Columbia, SC 29209
https://sc.edu/study/colleges_schools/medicine/research/research_facilities/instrumentation_resource_facility/index.php
RRID: RRID:SCR_024955
BD FACS Symphony A5 Cell Analyzer
BioRad BioPlex 100 and 200 Systems
BioRad GelDoc XR+ System and iMark Microplate Absorbance Reader
Discover Echo Revolve Microscope
Invitrogen EVOS FL Auto Cell Imaging System
JEOL 1400 Plus Transmission Electron Microscope
JL Shepherd and Associates Model 143-68 Blood Product Irradiator
Leica SP8 Multiphoton Confocal
Leica Stellaris 5 DIchroic
Leica Ultracut R Ultramicrotome
Logos Biosystems X-Clarity Tissue Clearing System
Mauna Kea Cellvizio In Vivo Confocal
Nikon E600 Widefield Epifluorescence and Darkfield Microscopy System
PerkinElmer IVIS Spectrum Fluorescence and Bioluminescence Imaging System
PerkinElmer Quantum GX microCT Imaging System
Qiagen Rotor-Gene Q rtPCR
Reichert U3 Ultramicrotome
Reichert-Jung 2030 Paraffin Rotary Microtomes
Tousimis Samdri PVT-3B Critical Point Dryer
Visual Sonics VEVO 3100 High Resolution In Vivo Imaging System
Zeiss Microm 505HN Cryostat
Zeiss SteREO Lumar V.12 Stereomicroscope
Analysis Workstations
Bioluminsecence Imaging
Brightfield Microscopy
Cell Culture
Cell Imaging
Clinical Imaging - Small Animal (luminescence/fluorescence)
Clinical Imaging - Small Animal (X-ray, Ultrasound, microCAT, MRI)
Confocal Microscopy
Digital PCR
Electron Microscopy
FACS Cell Sorting
Flow Cytometric Analysis
Flow Cytometry
H&E Staining
Histology
Image Aquisition
Immunofluorescence
Immunohistochemistry
In-vivo Imaging
Laser Capture Microdissection
Lattice Lightsheet
Light-sheet Microscopy
Live Cell Imaging
Microarray
MicroCT
Microscopy
Molecular Imaging
Multiphoton Microscopy
Negative Staining For TEM
Optical Imaging
Paraffin Embedding
Plate Reader
Real-time qPCR
Scanning Electron Microscopy
Staining
Tissue Culture
Transmission Electron Microscopy
Ultrasonic Imaging
1.) Waigi EW, Pernomian L, Crockett AM, Costa TJ, Townsend P Jr, Webb RC, McQuail JA, McCarthy CG, Hollis F, Wenceslau CF (2024 Jun 11). Vascular dysfunction occurs prior to the onset of amyloid pathology and Aβ plaque deposits colocalize with endothelial cells in the hippocampus of female APPswe/PSEN1dE9 mice GeroScience, 46(6), 5517-5536. . PMCID: 11493946.
2.) Pernomian L, Waigi EW, Nguyen V, Mohammed AD, da Costa TJ, Fontes MT, Kubinak JL, Aitken A, Biancardi VC, Sinclair DA, McCarthy CG, Wang Y, Tan W, Wenceslau CF (2024 May 21). A Single-Short Partial Reprogramming of the Endothelial Cells decreases Blood Pressure via attenuation of EndMT in Hypertensive Mice. bioRxiv : the preprint server for biology, (), . . PMID: 38826452.
Mission: By providing state-of-the-art biomedical instrumentation, the IRF seeks to facilitate the expansion of scientific knowledge and discovery in the USC School of Medicine Columbia and main campus research environments.
Purpose: As an integral component of the research and teaching mission of the University of South Carolina School of Medicine, the IRF houses several major pieces of state-of-the-art biotechnological equipment that provide investigation ranging from single cell and molecular level analysis to whole animal imaging. Additionally, the IRF maintains a full range of ancillary equipment available for sample preparation, image enhancement, and data analysis.
