University of California, Los Angeles
Contact Info:
Ken Yamauchi
610 Charles E Young Dr. South
TLSB 3000, Mail Code: 735704
Los Angeles, CA 90095
https://stemcell.ucla.edu/microscopy-core
Grants and Identifiers:
RRID: RRID:SCR_024914
Instrumentation:
(Equipment No Longer Active At this Facility)
Nikon AXR NSPARC super resolution inverted microscope
Confocal microscope provides enables collection of more data over wide area and down to deep regions in tissues. Its high sensitivity and high-speed scanning reduce phototoxicity to specimen and minimize damage. Equipped with image acquisition/analysis functions utilizing Artificial Intelligence (AI), the AX/AX R can efficiently acquire highly reliable data. Nikon Spatial Array Confocal (NSPARC) detector utilizes detector array to collect two-dimensional image at each scanned point. It adds additional potential to imaging by providing new level of ultra-low noise sensitive spatial detection, enabling improved lateral resolution of 1 airy unit/~230 nm and improved signal-to-noise ratio. [Product Link]
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(Equipment No Longer Active At this Facility)
Sartorius IncuCyte SX5 Live Cell Analysis System
Live-cell imaging and analysis system. It leverages up to five total fluorescence channels (up to three simultaneously) including long wavelength, low phototoxicity NIR channel that makes it ideal for long-term time-lapse experiments. Offers high-resolution imaging, real-time kinetic monitoring and automated analysis capabilities. [Product Link]
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(Equipment No Longer Active At this Facility)
ZEISS Axioscan 7 Digital Slide Scanner
High-throughput system designed for automated digitization of microscopy slides, primarily for life science research, clinical diagnosis, and geological applications. It excels at creating high-quality virtual slides from brightfield, fluorescence, and polarization microscopy samples. [Product Link]
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(Equipment No Longer Active At this Facility)
Zeiss LSM 700 microscope
Laser scanning confocal microscope designed for high-quality imaging of biological and material samples. Member of the seventh generation of confocal microscopes from Carl Zeiss. Point scanning confocal microscope., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. [Product Link]
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(Equipment No Longer Active At this Facility)
Zeiss LSM 780 Confocal Laser Scanning Microscope
Laser Scanning Microscopes (LSM) for high resolution imaging of biological or material samples. The compact scanning module can be fitted to an inverted (Axio Observer.Z1 RP or SP) or upright (Axio Imager.Z2, Axio Imager.M2 or Axio Examiner) microscope. [Product Link]
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(Equipment No Longer Active At this Facility)
Zeiss LSM 880 with Airyscan Confocal Laser Scanning Microscope
Fully enclosed laser scanning confocal imaging microscopefor heating and environmental control with media perfusion capabilities and CO2 control. It can be used for Live Cell Imaging, FRET and Anisotropy, FRAP and FLIP, FCS, Photoactivation/ -conversion. [Product Link]
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(Equipment No Longer Active At this Facility)
Zeiss LSM 900 with Airyscan 2
Laser scanning confocal microscope for multiplex imaging and analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. [Product Link]
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(Equipment No Longer Active At this Facility)
Sartorius IncuCyte SX5
Live cell imaging of cell cultures inside incubator
(Equipment No Longer Active At this Facility)
Yokogawa and Zeiss CSU-X1
CSU-X1 spinning disk confocal on Zeiss Observer Z1 stand
(Equipment No Longer Active At this Facility)
Yokogawa on Zeiss Observer Z1 stand CSU-X1 Spinning Disk Confocal
Spinning Disk Confocal Microscope
(Equipment No Longer Active At this Facility)
Zeiss AxioImager with Apotome Microscope
Upright wide-field fluorescence and transmitted light microscope
Zeiss LSM 880 with 2 photon
LSM 880 confocal on Observer Z1 with Coherent Ti-Sapphire 2 photon laser
Other Equipment
Services Provided:
3D & 4D Image Processing Stations
Computer-assisted Neuron Tracing And Analysis
Confocal/ Super Resolution Microscope
Differential Interference Contrast Microscopy
Fluorescence Microscope With Optical Sectioning Capability
Multiplexed Immunofluorescence
Shared Instrumentation Oversight & Maintenance
Spinning Disk Confocal Imaging
Relevant Publications:
Description:
The Microscopy Core is a collaboration of the Broad Stem Cell Research Center and the Department of Molecular, Cell and Developmental Biology. The Core's mission is to promote interdisciplinary and collaborative research across UCLA. The Core provides state-of-the-art, high resolution technologies for imaging and analyzing the molecular and structural organization of cells and tissue as well as bioengineered materials. The technologies available in this Core include confocal, wide-field fluorescence and live-cell imaging, as well as software for image analysis.
