Beth Israel Deaconess Medical Center
Contact Info:
Ashton Black
Beth Israel Deaconess Medical Center
330 Brookline Ave ESB01A-H
Boston, MA 02215
https://www.bidmc.org/research/core-facilities/ncrna-core
Grants and Identifiers:
RRID: RRID:SCR_024862
Instrumentation:
(Equipment No Longer Active At this Facility)
Precision Nanosystems The NanoAssemblr Ignite+
Microfluidics machine able to synthesize RNA-LNPs up to 60mL in volume.
Precision Nanosystems The NanoAssemblr Ignite+
Microfluidics machine able to synthesize LNPs up to 60mL in volume
(Equipment No Longer Active At this Facility)
Precision Nanosystems The NanoAssemblr Spark
The NanoAssemblr Spark has an operating nanoparticle formulation volume of 25 – 250 μL. By ensuring yields nearing 100%, the Spark is ideal for target validation screening and nanoparticle formulation development that involves scarce or expensive nucleic acid constructs and nanoparticle excipients.
Precision Nanosystems The NanoAssemblr Spark
Microfluidics machine able to synthesize small volumes of LNPs between 24-125 uL
Services Provided:
Relevant Publications:
Description:
The Delivery Unit offers training and services on the NanoAssemblr Spark, NanoAssemblr Ignite+, and Malvern Zetasizer for the purpose of synthesis and characterisation of Lipid Nanoparticles (LNPs). The Zetasizer is able to read zeta potential and size of particles, including exosomes, liposomes, and LNPs.
