University of Luxembourg

Contact Info:

Christian JAEGER

6, avenue du Swing

Belvaux L-4367

https://www.uni.lu/lcsb-en/facilities/metabolomics/

Grants and Identifiers:

RRID: RRID:SCR_024769

Instrumentation:

Services Provided:

Bioanalytical LC MS/MS

Consultations

Data Analysis

Data Analysis And Interpretation

Data Processing

Data Processing And Interpretation

GC-MS

IC-MS

LC-MS

Lipidomics

Mass Spectrometry

Mass Spectrometry - Small Molecules

Metabolomics

Sample Preparation

Sample Preparations And Metabolic Quenching

Small Molecule Compound Screening

Training

Relevant Publications:

1.) Patraskaki M, Seyedkatouli N, Schlicker L, Warmoes MO, Cordero-Maldonado ML, Heins-Marroquin U, Linster CL (2026 Mar). Unveiling Immune System Perturbations in Early Development Through Zebrafish Models of NADHX Repair Deficiency. Journal of inherited metabolic disease, 49(2), e70149. . PMCID: 12861718.

2.) Heins-Marroquin U, Hodzic Z, da Silva BS, Hendriks A, Gavotto F, Warmoes MO, Schlicker L, Omri S, Jäger C, Glaab E, Braverman NE, Cordero-Maldonado ML, Linster CL (2025 Nov 5). Pex1 loss-of-function in zebrafish is viable and recapitulates hallmarks of Zellweger spectrum disorders Frontiers in Molecular Neuroscience, 18(), 1634536. . PMCID: 12626956.

3.) Griffith CM, Conrotte JF, Paydar P, Xie X, Heins-Marroquin U, Gavotto F, Jäger C, Ellens KW, Linster CL (2025 Jun). CLYBL averts vitamin B(12) depletion by repairing malyl-CoA. Nature chemical biology, 21(6), 906-915. doi: 10.1038/s41589-025-01857-9. PMID: 40108300.

4.) Tsenkova M, Brauer M, Pozdeev VI, Kasakin M, Busi SB, Schmoetten M, Cheung D, Meyers M, Rodriguez F, Gaigneaux A, Koncina E, Gilson C, Schlicker L, Herebian D, Schmitz M, de Nies L, Mayatepek E, Haan S, de Beaufort C, Cramer T, Meiser J, Linster CL, Wilmes P, Letellier E (2025 Feb 20). Ketogenic diet suppresses colorectal cancer through the gut microbiome long chain fatty acid stearate Nature Communications, 16(), 1792. . PMCID: 11842570.

5.) Benzarti M, Neises L, Oudin A, Krötz C, Viry E, Gargiulo E, Pulido C, Schmoetten M, Pozdeev V, Lorenz NI, Ronellenfitsch MW, Sumpton D, Warmoes M, Jaeger C, Lesur A, Becker B, Moussay E, Paggetti J, Niclou SP, Letellier E, Meiser J (2024 Mar 26). PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle. Cell reports, 43(3), 113868. doi: 10.1016/j.celrep.2024.113868. PMID: 38421868.

Description:

The Metabolomics and Lipidomics Platform facilitates metabolism-related research, serving researchers from academia to industry in Luxembourg and beyond. We specialize in the analysis of small molecules within complex biological matrices. Our state-of-the-art analytical infrastructure and broad method portfolio accelerate scientific discoveries in the areas of biology and biomedicine.