Tulane University
Peter Dider, DVM, PhD
Tulane National Primate Research Center
18703 Three Rivers Road
Covington, LA 70433
https://tnprc.tulane.edu/anatomic-pathology-core
RRID: RRID:SCR_024606
Indica Labs Halo Image Analysis
Image analysis platform for quantitative analysis of digital pathology
Brightfield Microscopy
Cryostat Histology
Histology
Image Processing And Analysis
Microscopy
Necropsy
Special Stains Histology
Tissue Embed
Veterinary Pathology
1.) Currey J, Ellsworth C, Khatun MS, Wang C, Chen Z, Liu S, Midkiff C, Xiao M, Ren M, Liu F, Elgazzaz M, Fox S, Maness NJ, Rappaport J, Lazartigues E, Blair R, Kolls JK, Mauvais-Jarvis F, Qin X (2024 Oct). Upregulation of inflammatory genes and pathways links obesity to severe COVID-19. Biochimica et biophysica acta. Molecular basis of disease, 1870(7), 167322. . PMID: 38942338.
2.) Wang C, Khatun MS, Ellsworth CR, Chen Z, Islamuddin M, Nisperuza Vidal AK, Afaque Alam M, Liu S, Mccombs JE, Maness NJ, Blair RV, Kolls JK, Qin X (2024 Sep 17). Deficiency of Tlr7 and Irf7 in mice increases the severity of COVID-19 through the reduced interferon production. Communications biology, 7(1), 1162. . PMID: 39289468.
3.) Ellsworth CR, Chen Z, Xiao MT, Qian C, Wang C, Khatun MS, Liu S, Islamuddin M, Maness NJ, Halperin JA, Blair RV, Kolls JK, Tomlinson S, Qin X (2024 Sep 16). Enhanced complement activation and MAC formation accelerates severe COVID-19. Cellular and molecular life sciences : CMLS, 81(1), 405. . PMID: 39284944.
4.) MacLean A, Horn M, Midkiff C, Van Zandt A, Saied A (2024 Aug 5). Combination antiretroviral therapy prevents SIV- induced aging in the hippocampus and neurodegeneration throughout the brain. Research square, (), . . PMID: 39149452.
5.) Schulz ME, Akerstrom VL, Song K, Broyhill SE, Li M, Lambert MD, Goldberg TB, Kataru RP, Shin J, Braun SE, Norton CE, Czepielewski RS, Mehrara BJ, Domeier TL, Zawieja SD, Castorena-Gonzalez JA (2024 May 23). TRPV4-Expressing Tissue-Resident Macrophages Regulate the Function of Collecting Lymphatic Vessels via Thromboxane A2 Receptors in Lymphatic Muscle Cells. bioRxiv : the preprint server for biology, (), . . PMID: 38826322.
6.) Ellsworth CR, Wang C, Katz AR, Chen Z, Islamuddin M, Yang H, Scheuermann SE, Goff KA, Maness NJ, Blair RV, Kolls JK, Qin X (2024 Apr 15). Natural Killer Cells Do Not Attenuate a Mouse-Adapted SARS-CoV-2-Induced Disease in Rag2(-/-) Mice. Viruses, 16(4), . . PMID: 38675952.
7.) Parthasarathy G (2024). Fibroblast growth factor receptor inhibitors mitigate the neuropathogenicity of Borrelia burgdorferi or its remnants ex vivo. Frontiers in immunology, 15(), 1327416. . PMID: 38638441.
The Anatomic Pathology Core (APC) is responsible for post-mortem examinations, tissue collection and distribution, fixation, processing, slide preparation, routine and special staining, and diagnostic gross and histologic pathology services. The APC also processes and interprets biopsy specimens for both research and diagnostic purposes and provides tissue trimming, paraffin processing, sectioning, and routine and special staining for clinical and research staff and faculty. The APC works closely with clinical veterinarians, and through diagnostic pathology on biopsies and necropsies, plays a major role in monitoring and maintaining the health of the animals in the breeding colonies.
