University of Nebraska Medical Center

Contact Info:

Vikas Kumar

985819 Nebraska Medical Center

Omaha, NE 68198-5819

https://www.unmc.edu/vcr/cores/vcr-cores/mspcf/index.html

Grants and Identifiers:

RRID: RRID:SCR_012539

Instrumentation:

Services Provided:

Mass Spectrometry

Proteomics

Shared Instrumentation Oversight & Maintenance

Relevant Publications:

1.) Estrella LD, Xu X, White C, Manganaro JE, Sheldon L, Farmer T, Stauch KL (2025 Oct 15). The absence of Parkin in hTau mice leads to synaptic mitochondrial dysfunction, alterations to the synaptic proteome, and increased phosphorylated tau in the Hippocampus. Neurobiology of disease, 215(), 107084. doi: 10.1016/j.nbd.2025.107084. PMID: 40914434.

2.) Rohr RA, Schroder EA, Staab JD, Singh WP, Schroder CJ, Hatcher GD, McWilliams JT, Yang J, Bopp AE, Fatumoju LB, Wang Z, Dordick JS, Linhardt RJ, Zhang F, Liu J, Harris EN (2025 Apr). Characterization of Heparin Interactions With Recombinant Rodent Stabilin-2/Hyaluronic Acid Receptor for Endocytosis (HARE). Proteoglycan research, 3(2), . . PMID: 40895120.

3.) Shahreen N, Ahn J, Alsiyabi A, Chowdhury NB, Shinde D, Chaudhari SS, Bayles KW, Thomas VC, Saha R (2025 Jan 28). A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in Staphylococcus aureus. mSphere, 10(1), e0088324. . PMID: 39745366.

Description:

The mission of Mass Spectrometry and Proteomics Core Facility (MSPCF) at the University of Nebraska Medical Center is to enhance the capacity for research. Our main goals are: 1. to establish an integrated proteomics program to support researchers at the UNMC in their efforts to seek extramural funding, 2. to provide high quality services, to facilitate collaborative scientific effort with other institutions of higher education within State of Nebraska, and 3. to provide state-of-the-art environment for education of researchers in techniques of mass spectrometry and proteomics.