Sign In

Search |

Add/Edit My Facility

UT Austin Advanced Protein Therapeutics Core

The University of Texas at Austin

Contact Info:

Jennifer Maynard

200 E. Dean Keeton St.

Department of Chemical Engineering, UT Austin

Austin, TX 78712

https://biologics.utexas.edu/research/advanced-protein-therapeutics-core

Grants and Identifiers:

RRID: RRID:SCR_023740

Instrumentation:

Services Provided:

Antibody Characterization

Antibody Development

Antibody Drug Conjugates

Antibody Engineering

Antibody Production

Antibody Sequencing

Bispecific Antibodies

Cell Culture

Cell Imaging

Confocal Microscopy

ELISA

Enzyme Engineering

Flow Cytometric Analysis

Fluorescence Spectroscopy

High-throughput Screening

Nanobody Production

Protein Extraction/Purification

Protein Production

SDS-PAGE

Relevant Publications:

1.) Siles Alvarado N, Schuler M, Maguire C, Amengor DA, Nguyen AW, Wilen RE, Rogers J, Bazzi S, Caslin B, DiPasquale C, Abigania M, Olson E, Creaturo J, Hurley K, Triplett TA, Rousseau JF, Strakowski SM, Wylie D, Maynard JA, Ehrlich LIR, Melamed E (2025 May 2). SARS-CoV-2 humoral immune responses in convalescent individuals over 12 months reveal severity-dependent antibody dynamics. Communications medicine, 5(1), 149. . PMID: 40316665.


2.) Goldsmith JA, Nguyen AW, Wilen RE, Wijagkanalan W, McLellan JS, Maynard JA (2025 Apr 8). Structural basis for neutralizing antibody binding to pertussis toxin. Proceedings of the National Academy of Sciences of the United States of America, 122(14), e2419457122. . PMID: 40172968.


3.) Ma MT, Qerqez AN, Hill KR, Azouz LR, Youngblood HA, Hill SE, Ku Y, Peters DM, Maynard JA, Lieberman RL (2025 Jan). Antibody-mediated clearance of an ER-resident aggregate that causes glaucoma. PNAS nexus, 4(1), pgae556. . PMID: 39726989.


Description:

The UT Austin CPRIT-funded Advanced Protein Therapeutics Core (APT) catalyzes the translation of scientific discoveries into novel protein cancer therapies. We offer therapeutic antibody and enzyme discovery, engineering, and optimization services.