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Mouse Transgenic and Gene Targeting Core (TMF)

Emory University

Contact Info:

Karolina Nitsche

1760 Haygood Drive NE Health Sciences Research Bldg (HSRB-1), Suite E144

Atlanta, GA 30322

https://www.cores.emory.edu/tmf/index.html

Grants and Identifiers:

RRID: RRID:SCR_023535

Instrumentation:

Services Provided:

Assisted Reproductive Technologies (Rodent IVF, ICSI)

Cell Culture

Consultation

CRISPR

CRISPR Injection Services

CRISPR Rosa26 & CRISPR H11

CRISPR/Cas Project Design

Embryo Cryopreservation & Recovery Services

ES Cell Injection

ES Cell Technology (Mouse)

Fresh/Frozen Sperm IVF

Genome Engineering

Genotyping

Injection Of DNA Constructs

Karyotyping

Rederivation

Rederivation (Mouse)

Sperm Cryopreservation

Transgenics

Vitrification

Relevant Publications:

1.) Long AB, Wilson IM, Terry TT, Van Sciver RE, Caspary T (2025 Mar 26). ARL13B-Cerulean rescues Arl13b-null mouse from embryonic lethality and reveals a role for ARL13B in spermatogenesis bioRxiv, (), 2025.03.24.644968. . PMCID: 11974714.


Description:

The Mouse Transgenic and Gene Targeting Core (TMF), one of the Emory Integrated Core Facilities (EICF), is supported by the Georgia Clinical & Translational Science Alliance and the Emory University School of Medicine. We provide state-of-the-art equipment and expertise for generating and characterizing genetically altered mouse models. Please contact us to discuss your experimental needs.