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Emory Integrated Cellular Imaging Core (ICI)

Emory University

Contact Info:

Laura Fox-Goharioon

Winship Clinic C 1365 Clifton Road NE

Atlanta, GA 30322

https://www.cores.emory.edu/ici/index.html

Grants and Identifiers:

RRID: RRID:SCR_023534

Instrumentation:

Services Provided:

Relevant Publications:

1.) Kolachala VL, Maddipatla SC, Murthy S, Hwang Y, Dodd AF, Sharma G, Munasinghe S, Pelia RS, Venkateswaran S, Anbazhagan M, Koti T, Jhita N, Joshi GN, Lopez CA, Geem D, Yin H, Cutler DJ, Qiu P, Matthews JD, Kugathasan S (2025 Mar 10). Altered inflammatory mucosal signatures within their spatial and cellular context during active ileal Crohn’s disease JCI Insight, 10(5), e171783. . PMCID: 11949056.


2.) Gokhale A, Mendez-Vazquez H, Sampson MM, Moctezuma FG, Harbuzariu A, Sing A, Zlatic SA, Roberts AM, Prajapati M, Roberts BR, Bartnikas TB, Wood LB, Sloan SA, Faundez V, Werner E (2025 Feb 20). Mitochondrially Transcribed dsRNA Mediates Manganese-induced Neuroinflammation bioRxiv, (), 2025.02.16.638529. . PMCID: 11870567.


3.) Hrncir HR, Goodloe B, Bombin S, Hogan CB, Jadi O, Gracz AD (2025 Feb 15). Sox9 inhibits Activin A to promote biliary maturation and branching morphogenesis Nature Communications, 16(), 1667. . PMCID: 11830073.


4.) Butkovich LM, Yount ST, Allen AT, Seo EH, Swanson AM, Gourley SL (2025 Jan 13). Action inflexibility and compulsive-like behavior accompany neurobiological alterations in the anterior orbitofrontal cortex and associated striatal nuclei. Scientific reports, 15(1), 1863. . PMID: 39805892.


5.) Peterson RJ, Reed RC, Zamecnik CR, Sallam MA, Finbloom JA, Martinez FJ, Levy JM, Moonwiriyakit A, Desai TA, Koval M (2024 Dec 20). Apical integrins as a switchable target to regulate the epithelial barrier Journal of Cell Science, 137(24), jcs263580. . PMCID: 11795292.


6.) Tripathi AK, Dabeer S, Song J, Vikulina T, Roser-Page S, Alvarez JA, Archer DR, Weitzmann MN (2024 Dec 18). Hydroxyurea blunts mitochondrial energy metabolism and osteoblast and osteoclast differentiation exacerbating trabecular bone loss in sickle cell mice Cell Death & Disease, 15(12), 907. . PMCID: 11655664.


7.) Vazquez Cegla AJ, Jones KT, Cui G, Cottrill KA, Koval M, McCarty NA (2024 Oct 23). Effects of hyperglycemia on airway epithelial barrier function in WT and CF 16HBE cells. Scientific reports, 14(1), 25095. . PMID: 39443580.


8.) Anbazhagan M, Sharma G, Murthy S, Maddipatla SC, Kolachala VL, Dodd A, Randunne A, Cutler DJ, Kugathasan S, Matthews JD (2024 Oct 13). PTGER4 signaling regulates class IIa HDAC function and SPINK4 mRNA levels in rectal epithelial cells Cell Communication and Signaling : CCS, 22(), 493. . PMCID: 11472582.


9.) Bramlett SN, Foster SL, Weinshenker D, Hepler JR (2024 Sep 15). Endogenous Regulator of G protein Signaling 14 (RGS14) suppresses cocaine-induced emotionally motivated behaviors in female mice. bioRxiv : the preprint server for biology, (), . . PMID: 39314405.


10.) De Jesus Morales KJ, Santosa U, Brazhkina O, Rajurkar P, Jo H, Davis ME (2024 Sep). A Biomimetic Leaflet Scaffold for Aortic Valve Remodeling. Advanced healthcare materials, 13(23), e2303972. doi: 10.1002/adhm.202303972. PMID: 38692263.


11.) Berryhill BA, Gil-Gil T, Witzany C, Goldberg DA, Vega NM, Regoes RR, Levin BR (2024 Aug 23). The dynamics of Staphylococcal infection and their treatment with antibiotics and bacteriophage in the Galleria mellonella model system bioRxiv, (), 2024.08.23.609294. . PMCID: 11370618.


12.) Janto NV, Gleizes AR, Sun S, Ari G, Gracz AD (2024 Aug 9). Tritrichomonas muris sensitizes the intestinal epithelium to doxorubicin-induced apoptosis bioRxiv, (), 2024.08.08.607206. . PMCID: 11326309.


13.) Adebambo TH, Flores MF, Zhang SL, Lerit DA (2024 Aug 7). Arsenic impairs Drosophila neural stem cell mitotic progression and sleep behavior in a tauopathy model bioRxiv, (), 2024.08.05.606375. . PMCID: 11326188.


14.) Lancaster CL, Yalamanchili PS, Goldy JN, Leung SW, Corbett AH, Moberg KH (2024 Jul 22). The RNA-binding protein Nab2 regulates levels of the RhoGEF Trio to govern axon and dendrite morphology Molecular Biology of the Cell, 35(8), ar109. . PMCID: 11321036.


15.) Bramlett SN, Fitzmaurice SM, Harbin NH, Yan W, Bandlamudi C, Van Doorn GE, Smith Y, Hepler JR (2024 Jun 27). Regulator of G Protein Signaling 14 protein expression profile in the adult mouse brain. bioRxiv : the preprint server for biology, (), . . PMID: 38979272.


16.) Linen SR, Chang NH, Hess EJ, Stanley GB, Waiblinger C (2024 Jun 6). Sensory-Behavioral Deficits in Parkinson’s Disease: Insights from a 6-OHDA Mouse Model bioRxiv, (), 2024.06.05.597339. . PMCID: 11185599.


17.) Zimmer SE, Giang W, Levental I, Kowalczyk AP (2024 Apr 26). The transmembrane domain of the desmosomal cadherin desmoglein-1 governs lipid raft association to promote desmosome adhesive strength. bioRxiv : the preprint server for biology, (), . . PMID: 38712246.


18.) Yoon SB, Chen L, Robinson IE, Khatib TO, Arthur RA, Claussen H, Zohbi NM, Wu H, Mouw JK, Marcus AI (2024 Mar 29). Subpopulation commensalism promotes Rac1-dependent invasion of single cells via laminin-332 The Journal of Cell Biology, 223(6), e202308080. . PMCID: 10982113.


19.) Knippler CM, Arnst JL, Robinson IE, Matsuk V, Khatib TO, Harvey RD, Shanmugam M, Mouw JK, Fu H, Ganesh T, Marcus AI (2024 Mar 27). Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion iScience, 27(4), 109591. . PMCID: 11022046.


20.) Wills R, Shirke R, Hrncir H, Talbott JM, Sad K, Spangle JM, Gracz AD, Raj M (2024 Mar 19). Tunable fluorescent probes for detecting aldehydes in living systems Chemical Science, 15(13), 4763-4769. . PMCID: 10966992.


21.) Hrncir HR, Bombin S, Goodloe B, Hogan CB, Jadi O, Gracz AD (2024 Jan 16). Sox9 links biliary maturation to branching morphogenesis bioRxiv, (), 2024.01.15.574730. . PMCID: 10827067.


22.) Hwang J, Yanagisawa H, Davis KC, Hunter EL, Fox LA, Jimenez AR, Goodwin RE, Gordon SA, Stuart CDE, Bower R, Porter ME, Dutcher SK, Sale WS, Lechtreck KF, Alford LM (2024 Jan 15). Assembly of FAP93 at the proximal axoneme in Chlamydomonas cilia. Cytoskeleton (Hoboken, N.J.), (), . doi: 10.1002/cm.21818. PMID: 38224153.


23.) Banerjee S, Lu S, Jain A, Wang I, Tao H, Srinivasan S, Nemeth E, He P (2023 Nov 29). Targeting PKC alleviates iron overload in diabetes and hemochromatosis. bioRxiv : the preprint server for biology, (), . . PMID: 38076948.


Description:

The Integrated Cellular Imaging Core, one of the Emory Integrated Core Facilities (EICF), is supported by the Winship Cancer Institute, Emory + Children's Pediatric Research Center, and the Emory University School of Medicine. We help investigators use the latest light microscopy in their research. Please contact us so that we can discuss your experimental needs.