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DCC - Microscopy Shared Resource

Dartmouth College

Contact Info:

Radu V Stan

One Medical Center Drive

Dartmouth Cancer Center, Borwell 338 West

Lebanon, NH 03756

https://cancer.dartmouth.edu/scientists-researchers/microscopy-resource

Grants and Identifiers:

RRID: RRID:SCR_023478

Instrumentation:

BioTek Cytation 5 Cell Imaging Multi-Mode Reader

Multi-mode plate reader that offers up to 60x magnification in fluorescence, brightfield, high contrast brightfield, color brightfield and phase contrast for maximum applications reach. The multi-mode detection modules include filter- and monochromator-based fluorescence detection, luminescence and UV-Vis absorbance detection. [Product Link]

RRID:SCR_019732

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Olympus IX73 Inverted Microscope

Olympus IX73 inverted microscope has been integrated into our IXplore systems. IXplore Systems are designed to provide solutions-based packages that suit your research application needs. [Product Link]

RRID:SCR_020346

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Olympus IX83 Automated Fluorescence Microscope

The Olympus IX83 inverted microscope has been integrated into our IXplore systems. IXplore Systems are designed to provide solutions-based packages that suit your research application needs. [Product Link]

RRID:SCR_020344

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(Equipment No Longer Active At this Facility)

Zeiss LSM 880 with Airyscan Confocal Laser Scanning Microscope

Fully enclosed laser scanning confocal imaging microscopefor heating and environmental control with media perfusion capabilities and CO2 control. It can be used for Live Cell Imaging, FRET and Anisotropy, FRAP and FLIP, FCS, Photoactivation/ -conversion. [Product Link]

RRID:SCR_020925

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Akoya Vectra 3

automated fluorescence slide scanner

Alveole PRIMO

UV based micropatterning and microfabrication device

Zeiss LSM 800 with Airyscan Confocal Laser Scanning Microscope

Confocal Laser Scanning Microscope with Airyscan detector

Services Provided:

Cell Imaging

Confocal Microscopy

Confocal/ Super Resolution Microscope

Fluorescence Microscope With Optical Sectioning Capability

Image Aquisition

Live Cell Imaging

Microscopy

Multiplex Fluorescence

Optical Imaging

Photolithography

Whole Slide Imaging

Widefield Microscopy

Relevant Publications:

1.) Saxe R, Stuart H, Marshall A, Abdullahi F, Chen Z, Emiliani F, McKenna A (2025 Mar 3). Hierarchical Lineage Tracing Reveals Diverse Pathways of AML Treatment Resistance bioRxiv, (), 2025.02.27.640600. . PMCID: 11908168.


Description:

Light microscopy imaging facility within the Dartmouth Cancer Center. Services offered: confocal microscopy with Airyscan, multispectral imaging slide scanner, high thoughput brightfield and multichannel fluorescence microscopy of live cells, multichannel TIRF microscopy, photopatterning and microfabrication.