University of Iowa
Kevin Knudtson
Genomics Division, 116 EMRB
Iowa City, IA 52242
https://medicine.uiowa.edu/humangenetics/genomics-division
RRID: RRID:SCR_023422
10x Genomics
ChIP-Seq
Digital PCR
DNA Analysis
Droplet Digital PCR
Genomics
Microarray
Mycoplasma Detection
Nanopore Sequencing
Nanostring
Nanostring NCounter
Real-time qPCR
RNA analysis
RNAseq
Seq-Well
Sequencing - Capillary Sequencing
Sequencing - DNA Sequencing
Sequencing - Next Generation Sequencing (NGS)
Single-Cell Analysis
Single-cell Sequencing
Whole Genome Sequencing
1.) Guo DF, Luo Z, Olson A, Morgan DA, Newell EA, Rahmouni K (2025 Dec). SerpinA3N in leptin-sensitive neurons is required for energy and glucose homeostasis and autonomic regulation. Metabolism: clinical and experimental, 173(), 156387. doi: 10.1016/j.metabol.2025.156387. PMID: 40935321.
2.) Bierstedt KC, Lin MH, Yu W, Cooney AL, Goodell BJ, Gong H, Pezzulo AA, Sinn PL, Xie Y (2025 Nov 21). Porcine airway tissue explant culture at a hydrogel-air interface to model submucosal glands in cystic fibrosis progression and therapy. Science advances, 11(47), eady4866. . PMCID: 12629201.
3.) Xiang J, McLinden JH, Chang Q, Fosdick M, Haim H, Ploss A, Hottel W, Bhattarai N, Tamura T, Zhang J, Houtman JCD, Stapleton JT (2025 Nov 14). Characterization of Serotype-Specific Dengue Virus T-Cell Inhibition. The Journal of infectious diseases, 232(5), 1228-1238. . PMID: 40336275.
4.) Cheung PH, Chan P, Yang H, Honne S, Kim B, Perlman S, Wu L (2025 Oct 26). SAMHD1 promotes SARS-CoV-2 infection by enhancing HNF1-dependent ACE2 expression in lung epithelial cells. bioRxiv : the preprint server for biology, (), . . PMCID: 12633470.
5.) Resch J, Li Y, Butler T, Nardone S, Jacobs C, Douglass A, Madara J, McDonough M, Tao J, Lowenstein E, Wang L, Pant D, Walker S, Wang A, Srinivasan H, Yang Z, Campbell J, Tsai LT, Lowell B (2025 Oct 21). A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types. Research square, (), . . PMCID: 12633530.
6.) Scalora N, DeWane G, Drebot Y, Khan AA, Sinha S, Ghosh K, Robinson D, Cogswell P, Bellizzi AM, Snow AN, Breheny P, Chimenti MS, Tanas MR (2025 Oct 10). EHE cell cultures are a platform for mechanistic and therapeutic investigation. Scientific reports, 15(1), 35516. . PMCID: 12514230.
7.) Shin MR, Firouzshahi N, Liddiard G, Weis M, Simmering J, Glykys J, Schultz M, Hefti MM (2025 Oct 3). Adaptive Suppression of MAPT Transcription Maintains Tau Proteostasis in Developing Human Neurons. Research square, (), . . PMCID: 12622181.
8.) Llopart A, Pettie N, Ryon A, Comeron JM (2025 Oct). A high-resolution crossover landscape in Drosophila santomea reveals rapid and concerted evolution of multiple properties of crossing over control. PLoS genetics, 21(10), e1011885. . PMCID: 12500166.
9.) Gourronc FA, Ahmann MI, Rebagliati MR, Klingelhutz AJ (2025 Sep 27). ACE2-Mediated Infection of Immortalized Human Visceral Adipocytes by SARS-CoV-2. Viruses, 17(10), . . PMCID: 12567992.
10.) Basu B, Breese NM, Lombardi S, Wang H, Li X, Tiburcio D, Niemasz Z, Beyer SE, Dean LE, Marek RF, Toborek M, Lehmler HJ, Chatterjee S (2025 Jul 26). Spatial transcriptomic profiling uncovers the molecular effects of the neurotoxicant polychlorinated biphenyls (PCBs) in the brains of adult mice. bioRxiv : the preprint server for biology, (), . . PMID: 40777386.
11.) Stone NE, Bohrer LR, Mullin NK, Berthold A, Wright AT, Han IC, Stone EM, Mullins RF, Tucker BA (2025 Jul 22). Device-free isolation of photoreceptor cells from patient iPSC-derived retinal organoids. JCI insight, 10(14), . . PMID: 40504625.
12.) Lozano LP, Jensen R, Jennisch M, Pandala NG, Jamshidi F, Boldt HC, Tucker BA, Binkley EM (2025 May). Genetics and current research models of Mendelian tumor predisposition syndromes with ocular involvement. Progress in retinal and eye research, 106(), 101359. . PMCID: 12646286.
13.) Scalora N, DeWane G, Drebot Y, Khan AA, Sinha S, Ghosh K, Robinson D, Cogswell P, Bellizzi AM, Snow AN, Breheny P, Chimenti MS, Tanas MR (2025 Mar 27). EHE cell cultures: a platform for mechanistic and therapeutic investigation. bioRxiv : the preprint server for biology, (), . . PMID: 40196670.
14.) Mukherjee U, Basu B, Beyer SE, Ghodsi S, Robillard N, Vanrobaeys Y, Taylor EB, Abel T, Chatterjee S (2025 Feb 19). Histone Lysine Crotonylation Regulates Long-Term Memory Storage. bioRxiv : the preprint server for biology, (), . . PMID: 40027819.
15.) Hudachek CL, Zhanbolat B, Chen Y, Wilson ME (2025). Human macrophages release exosomes containing anti-inflammatory microRNAs after phagocytosis of Leishmania infantum. Frontiers in immunology, 16(), 1593829. . PMCID: 12727609.
16.) Bembenek BM, Joshy A, Offer SM (2024 Nov). Lethal 5-Fluorouracil Toxicity in a Carrier of DPYD c.704G>A (p.R235Q). JCO precision oncology, 8(), e2400294. . PMCID: 12643069.
Genomics Division provides a broad spectrum of resources designed to make the techniques of genomics, functional genomics, and recombinant DNA technology readily available to the University of Iowa research and clinical communities and outside users. These resources include Next Generation sequencing, single cell analysis, spatial transcriptomics, Sanger Sequencing, qPCR, digital PCR, Nanostring, and microarray analysis.
