Centre for Genomic Regulation
Contact Info:
Eduard Sabido
88 Dr. Aiguader St.
Barcelona
https://www.crg.eu/en/programmes-groups/crgupf-proteomics-unit
Grants and Identifiers:
RRID: RRID:SCR_023377
Instrumentation:
EASY-nLC 1200 System
System provides peak performance for nanoflow applications up to 1200 bar. Dual in-line flow sensors before solvent mixing give excellent gradient precision. Its intuitive software facilitates rapid method setup and immediate system control. [Product Link]
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Thermo Exploris 240 LC/MS system
Exploris 240 system is hybrid quadrupole Orbitrap mass spectrometer with Waters H-Class Acquity, ZipChip, and DART front ends. Flexible platform for wide range of small molecule and intact protein analyses. [Product Link]
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Thermo Scientific Orbitrap Astral Mass Spectrometer
Mass spectrometer combines faster throughput, deeper coverage, and higher sensitivity while delivering accurate and precise quantitation over high dynamic range. Suited for accurate and precise quantitation at unprecedented depth of coverage and higher throughput from single cells to bulk samples. [Product Link]
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Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
Mass spectrometer designed for most difficult analytical challenges. Incorporates inventions in ion transmission and control, extended m/z range, and real-time decision making. System suited for proteomics, structural biology, small-molecule, and biopharmaceutical characterization experiments. [Product Link]
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Thermo Scientific Vanquish Neo UHPLC System
Low flow, high-sensitivity Liquid Chromatography-Mass Spectrometry system delivers retention time precision from nano up to 100 μL/min at pressures up to 1500 bar for reproducible nano-, capillary-, and micro-flow LC-MS. [Product Link]
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Services Provided:
Analysis Of (ribo-)nucleoside Modifications
Label Free Narrow Window DIA For Proteomics And PTMs
Label Free Quantitative Proteomics
Protein Interactions (IP/MS, AP/MS, Proximity Labeling, DNA-protein Interactions, Chemoproteomics)
Protein Post-Translational Modification Profiling (TMT, Label-Free)
Relevant Publications:
Description:
The Proteomics Unit is a joint effort of the Universitat Pompeu Fabra and the Center of Genomic Regulation to create an innovative research infrastructure with a high-level of excellence and sustainability to support scientists in the biomedical field. The activities of the Proteomics Unit are focused onto the provision of high-quality proteomics services with strong added-value to the research community by offering state-of-the-art methods, advise and expertise to support basic and translational researchers; developing new methods and techniques that keep the unit up to date and at the forefront of the proteomics field; and training the community and actively disseminating proteomics science and methods. The Proteomics Unit is part of the Spanish National Infrastructure for Omics Technologies (ICTS OmicsTech) in the Spanish Roadmap of Research Infrastructures.
