Van Andel Institute
Scott Bechaz
333 Bostwick Ave
Grand Rapids, MI 49503
https://vivariumandtransgenicscore.vai.org/
RRID: RRID:SCR_023211
In-vivo Imaging
Irradiation
Necropsy
Rotarod
Surgical Services
Tail Biopsy
Training
Xenograft / Xenotransplantation
1.) Xue Z, Xuan H, Lau K, Su Y, Wegener M, Li K, Turner L, Adams M, Shi X, Wen H (2025 Mar 14). Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development Nature Communications, 16(), 2531. . PMCID: 11909213.
2.) Panzeri I, Fagnocchi L, Apostle S, Tompkins M, Wolfrum E, Madaj Z, Hostetter G, Liu Y, Schaefer K, Yang CH, Bergsma A, Drougard A, Dror E, Chandler DP, Schramek D, Triche TJ Jr, Pospisilik JA (2025 Jan 24). TRIM28-dependent developmental heterogeneity determines cancer susceptibility through distinct epigenetic states Nature Cancer, 6(2), 385-403. . PMCID: 11864977.
3.) Panzeri I, Madaj Z, Fagnocchi L, Apostle S, Tompkins M, Hostetter G, Pospisilik JA (2024 Oct 16). Chronic obesity does not alter cancer survival in Tp53R270H/+ mice bioRxiv, (), 2024.10.14.618190. . PMCID: 11507782.
4.) Panzeri I, Madaj Z, Fagnocchi L, Apostle S, Tompkins M, Hostetter G, Pospisilik JA (2024 Oct 16). Chronic obesity does not alter cancer survival in Tp53 (R270H/+) mice. bioRxiv : the preprint server for biology, (), . . PMID: 39463991.
5.) Longo J, DeCamp LM, Oswald BM, Teis R, Reyes-Oliveras A, Dahabieh MS, Ellis AE, Vincent MP, Damico H, Gallik KL, Compton SE, Capan CD, Williams KS, Esquibel CR, Madaj ZB, Lee H, Roy DG, Krawczyk CM, Haab BB, Sheldon RD, Jones RG (2024 Oct 14). Glucose-dependent glycosphingolipid biosynthesis fuels CD8(+) T cell function and tumor control. bioRxiv : the preprint server for biology, (), . . PMID: 39464161.
6.) Xue Z, Qin L, Xuan H, Luo K, Huang M, Xie L, Su Y, Xu L, Harsh J, Dale B, Shi X, Chen X, Kaniskan HÜ, Jin J, Wen H (2024 Aug 28). A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression Science Advances, 10(35), eado1432. . PMCID: 11352836.
7.) Guak H, Weiland M, Ark AV, Zhai L, Lau K, Corrado M, Davidson P, Asiedu E, Mabvakure B, Compton S, DeCamp L, Scullion CA, Jones RG, Nowinski SM, Krawczyk CM (2024 Jul 24). Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function Cell reports, 43(8), 114506. . PMCID: 11416765.
8.) Yue F, Ku AT, Stevens PD, Michalski MN, Jiang W, Tu J, Shi Z, Dou Y, Wang Y, Feng XH, Hostetter G, Wu X, Huang S, Shroyer NF, Zhang B, Williams BO, Liu Q, Lin X, Li Y (2024 Jan 11). Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer bioRxiv, (), 2024.01.10.574969. . PMCID: 10802575.
9.) Diegel CR, Michalski MN, Williams BO (2023 Oct 15). β-catenin-dependent High Bone Mass Induced by Loss of APC in Osteoblasts Does Not Require Lrp5 or Lrp6 microPublication Biology, 2023(), 10.17912/micropub.biology.001000. . PMCID: 10613880.
10.) Panzeri I, Fagnocchi L, Apostle S, Tompkins M, Wolfrum E, Madaj Z, Hostetter G, Liu Y, Schaefer K, Chih-Hsiang Y, Bergsma A, Drougard A, Dror E, Chandler D, Schramek D, Triche TJ Jr, Pospisilik JA (2023 Sep 15). Developmental priming of cancer susceptibility bioRxiv, (), 2023.09.12.557446. . PMCID: 10515831.
Van Andel Institute is committed to conducting exceptional animal research in an ethical and responsible manner to further science and improve the health of society. VAI’s Vivarium Core provides and supports the gold standard of high-quality mouse, rat and zebrafish modeling services for VAI investigators, collaborators and the greater research community. VAI’s Vivarium is a state-of-the-art facility that includes a high-containment barrier. All procedures are conducted according to the National Institutes of Health’s Guide for the Care and Use of Laboratory Animals. The Institute is accredited at the highest standard of care through the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International.