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Biosafety Level 3

University of Rochester Medical Center

Contact Info:

Martin Pavelka, PhD

601 Elmwood Avenue

University of Rochester Medical Center

Rochester, NY 14642

https://www.urmc.rochester.edu/research/bsl3-core.aspx

Grants and Identifiers:

RRID: RRID:SCR_023178

Instrumentation:

Services Provided:

Relevant Publications:

1.) Wlodarchak N, Teachout N, Beczkiewicz J, Procknow R, Schaenzer AJ, Satyshur K, Pavelka M, Zuercher W, Drewry D, Sauer JD, Striker R (2018 Nov 5). In Silico Screen and Structural Analysis Identifies Bacterial Kinase Inhibitors which Act with β-Lactams To Inhibit Mycobacterial Growth. Molecular pharmaceutics, 15(11), 5410-5426. . ID: 30285456.


2.) LoVullo ED, Wright LF, Isabella V, Huntley JF, Pavelka MS Jr (2015 May). Revisiting the Gram-negative lipoprotein paradigm. Journal of bacteriology, 197(10), 1705-15. . ID: 25755189.


3.) Feiler C, Fisher AC, Boock JT, Marrichi MJ, Wright L, Schmidpeter PA, Blankenfeldt W, Pavelka M, DeLisa MP (2013). Directed evolution of Mycobacterium tuberculosis β-lactamase reveals gatekeeper residue that regulates antibiotic resistance and catalytic efficiency. PloS one, 8(9), e73123. . ID: 24023821.


4.) LoVullo ED, Molins-Schneekloth CR, Schweizer HP, Pavelka MS (2009 Apr). Single-copy chromosomal integration systems for Francisella tularensis. Microbiology (Reading, England), 155(), 1152-1163. . ID: 19332817.


5.) LoVullo ED, Sherrill LA, Pavelka MS Jr (2009 Feb). Improved shuttle vectors for Francisella tularensis genetics. FEMS microbiology letters, 291(1), 95-102. . ID: 19067747.


6.) LoVullo ED, Sherrill LA, Perez LL, Pavelka MS (2006 Nov). Genetic tools for highly pathogenic Francisella tularensis subsp. tularensis. Microbiology (Reading, England), 152(), 3425-3435. doi: 10.1099/mic.0.29121-0. ID: 17074911.


Description:

The Biosafety Level 3 (BSL3) core facility is available for use by any researcher at the university whose work requires the manipulation of biological agents that may cause serious or potentially lethal disease as a result of exposure by the inhalation route.