Salk Institute for Biological Studies

Contact Info:

John Naughton

10010 N. Torrey Pines Rd.

La Jolla, CA 92037

http://www.salk.edu/science/core-facilities/gene-transfer-targeting-and-therapeutics-core/

Grants and Identifiers:

RRID: RRID:SCR_014847

Instrumentation:

Services Provided:

Relevant Publications:

1.) Faulkner RL, Wall NR, Callaway EM, Cline HT (2021 Jun 7). Application of Recombinant Rabies Virus to Xenopus Tadpole Brain. eNeuro, 8(4), . . PMID: 34099488.

2.) Aoki S, Smith JB, Li H, Yan X, Igarashi M, Coulon P, Wickens JR, Ruigrok TJ, Jin X (2019 Sep 6). An open cortico-basal ganglia loop allows limbic control over motor output via the nigrothalamic pathway. eLife, 8(), . . PMID: 31490123.

3.) Klug JR, Engelhardt MD, Cadman CN, Li H, Smith JB, Ayala S, Williams EW, Hoffman H, Jin X (2018 May 1). Differential inputs to striatal cholinergic and parvalbumin interneurons imply functional distinctions. eLife, 7(), . . PMID: 29714166.

4.) Lucas EK, Jegarl AM, Morishita H, Clem RL (2016 Aug 3). Multimodal and Site-Specific Plasticity of Amygdala Parvalbumin Interneurons after Fear Learning. Neuron, 91(3), 629-43. . PMID: 27427462.

Description:

Core facility that provides consultation on the use of viral vector technologies as well as custom design and production services for multiple vector types. The GT3 facilitates the use of these research tools by Salk researchers and others across diverse fields of study such as systems neuroscience, stem cell biology, metabolism, ageing, cancer biology and gene therapy. The GT3 core is a designated Cancer Center Council (C3) core facility. Cancer Center members from participating C3 institutes have preferential rates.