University of Arizona
Andrei Astashkin
1306 E. University Blvd
Tucson, AZ 85719
https://cbc.arizona.edu/rss/epr-facility
RRID: RRID:SCR_022883
Paramagnetic Resonance
Spectroscopy
Structure Determination
1.) Smith TE, Astashkin AV, Albert DR, Rajaseelan E (2023 Jan). [(1,2,5,6-η)-Cyclo-octa-1,5-diene](4-isopropyl-1-methyl-1,2,4-triazol-5-yl-idene)(tri-phenyl-phos-phane)iridium(I) tetra-fluorido-borate di-chloro-methane 0.8-solvate. IUCrData, 8(), x230064. . ID: 36794052.
2.) Wu W, Sung YS, Tomat E (2022 Dec 12). Thiol-Reactive Arylsulfonate Masks for Phenolate Donors in Antiproliferative Iron Prochelators. Inorganic chemistry, 61(49), 19974-19982. doi: 10.1021/acs.inorgchem.2c03250. ID: 36455205.
3.) Tomat E, Curtis CJ (2021 Dec 21). Biopyrrin Pigments: From Heme Metabolites to Redox-Active Ligands and Luminescent Radicals. Accounts of chemical research, 54(24), 4584-4594. doi: 10.1021/acs.accounts.1c00613. ID: 34870973.
4.) Sung YS, Wu W, Ewbank MA, Utterback RD, Marty MT, Tomat E (2021 Sep 16). Albumin Conjugates of Thiosemicarbazone and Imidazole-2-thione Prochelators: Iron Coordination and Antiproliferative Activity. ChemMedChem, 16(18), 2764-2768. . ID: 33974730.
5.) Curtis CJ, Astashkin AV, Conradie J, Ghosh A, Tomat E (2021 Aug 16). Ligand-Centered Triplet Diradical Supported by a Binuclear Palladium(II) Dipyrrindione. Inorganic chemistry, 60(16), 12457-12466. doi: 10.1021/acs.inorgchem.1c01691. ID: 34347474.
6.) Gaur K, Pérez Otero SC, Benjamín-Rivera JA, Rodríguez I, Loza-Rosas SA, Vázquez Salgado AM, Akam EA, Hernández-Matias L, Sharma RK, Alicea N, Kowaleff M, Washington AV, Astashkin AV, Tomat E, Tinoco AD (2021 Jun 28). Iron Chelator Transmetalative Approach to Inhibit Human Ribonucleotide Reductase. JACS Au, 1(6), 865-878. . ID: 34240081.
7.) Shaikh AC, Veleta JM, Moutet J, Gianetti TL (2021 Feb 8). Trioxatriangulenium (TOTA(+)) as a robust carbon-based Lewis acid in frustrated Lewis pair chemistry. Chemical science, 12(13), 4841-4849. . ID: 34168760.
8.) Shaikh AC, Moutet J, Veleta JM, Hossain MM, Bloch J, Astashkin AV, Gianetti TL (2020 Sep 23). Persistent, highly localized, and tunable [4]helicene radicals. Chemical science, 11(40), 11060-11067. doi: 10.1039/d0sc04850j. ID: 34123196.
9.) Astashkin AV, Utterback RD, Sung YS, Tomat E (2020 Aug 17). Iron Complexes of an Antiproliferative Aroyl Hydrazone: Characterization of Three Protonation States by Electron Paramagnetic Resonance Methods. Inorganic chemistry, 59(16), 11377-11384. . ID: 32799490.
10.) Ingersol LJ, Yang J, Kc K, Pokhrel A, Astashkin AV, Weiner JH, Johnston CA, Kirk ML (2020 Feb 12). Addressing Ligand-Based Redox in Molybdenum-Dependent Methionine Sulfoxide Reductase. Journal of the American Chemical Society, 142(6), 2721-2725. . ID: 31989824.
11.) Astashkin AV, Li J, Zheng H, Feng C (2019 Aug 15). Positional Distributions of the Tethered Modules in Nitric Oxide Synthase: Monte Carlo Calculations and Pulsed EPR Measurements. The journal of physical chemistry. A, 123(32), 7075-7086. . ID: 31310526.
12.) Mejias SH , Bahrami-Dizicheh Z , Liutkus M , Sommer DJ , Astashkin A , Kodis G , Ghirlanda G , Cortajarena AL (2019 Mar 14). Repeat proteins as versatile scaffolds for arrays of redox-active FeS clusters. Chemical communications (Cambridge, England), 55(23), 3319-3322. . ID: 30829362.
13.) Gautam R, Petritis SJ, Astashkin AV, Tomat E (2018 Dec 17). Paramagnetism and Fluorescence of Zinc(II) Tripyrrindione: A Luminescent Radical Based on a Redox-Active Biopyrrin. Inorganic chemistry, 57(24), 15240-15246. doi: 10.1021/acs.inorgchem.8b02532. ID: 30418755.
14.) Astashkin AV, Li J, Zheng H, Miao Y, Feng C (2018 Jul). A docked state conformational dynamics model to explain the ionic strength dependence of FMN - heme electron transfer in nitric oxide synthase. Journal of inorganic biochemistry, 184(), 146-155. . ID: 29751215.
15.) Gautam R, Astashkin AV, Chang TM, Shearer J, Tomat E (2017 Jun 5). Interactions of Metal-Based and Ligand-Based Electronic Spins in Neutral Tripyrrindione π Dimers. Inorganic chemistry, 56(11), 6755-6762. . ID: 28497967.
16.) Boros E, Srinivas R, Kim HK, Raitsimring AM, Astashkin AV, Poluektov OG, Niklas J, Horning AD, Tidor B, Caravan P (2017 May 8). Intramolecular Hydrogen Bonding Restricts Gd-Aqua-Ligand Dynamics. Angewandte Chemie (International ed. in English), 56(20), 5603-5606. . ID: 28398613.
17.) Astashkin AV (2015). Mapping the Structure of Metalloproteins with RIDME. Methods in enzymology, 563(), 251-84. doi: 10.1016/bs.mie.2015.06.031. ID: 26478488.
A research facility for studying paramagnetic centers by continuous wave and pulsed EPR techniques to obtain information on the electronic, chemical, and geometric molecular structures.
