University of Warsaw
Dorota Adamska
Centre of New Technologies, University of Warsaw, Banacha 2c
Warsaw 02-097
https://cent.uw.edu.pl/en/core-facilities/genomics-core-facility/
RRID: RRID:SCR_022718
2100 Bioanalyzer Instrument
The 2100 Bioanalyzer system is an automated electrophoresis tool that provides precise analytical evaluation of various samples types in many workflows, including next generation sequencing (NGS), gene expression, biopharmaceutical, and gene editing research. Digital data is provided in a timely manner and delivers objective assessment of sizing, quantitation, integrity and purity from DNA, RNA, and proteins. Minimal sample volumes are required for an accurate result, and the data may be exported in a many different formats for ease-of-use. [Product Link]
RRID:SCR_018043
Agilent 5200 Fragment Analyzer System
Fragment Analyzer System allows you to separate 12 samples in parallel in as little as 15 minutes. [Product Link]
RRID:SCR_019417
Illumina MiSeq System
Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 × 300 bp read lengths. [Product Link]
RRID:SCR_020134
Illumina NextSeq 550 System
With tunable output and high data quality, it provides flexible power you need for whole genome, transcriptome, and targeted resequencing plus ability to scan microarrays including Infinium MethylationEPIC BeadChip and other select BeadChips. [Product Link]
RRID:SCR_020141
Illumina NovaSeq 6000 Sequencing System
Unleashes groundbreaking innovations that leverage our technology Now you can get scalable throughput and flexibility for virtually any sequencing method, genome, and scale of project. [Product Link]
RRID:SCR_020150
Roche Light Cycler 480 qPCR Real Time PCR System
Real time PCR device that allows use of additional thermal block cycler units 96 well and 384 well format. [Product Link]
RRID:SCR_018626
Agilent TapeStation 2200
Covaris M220 Focused-Ultrasonicator
Covaris S220 Focused-Ultrasonicator
Amino Acid Analysis
ATAC-Seq
CDNA Synthesis
ChIP-Seq
Consultation
Customized Protocols
Data Analysis
Data Processing
Data Visualization
DNA Analysis
Genome/Transcriptome Assembly And Annotation
Genomics
Library Services
Metagenomics Analysis
Metatranscriptomics
Protocol Development
RNA analysis
RNA Integrity
RNAseq
Sequencing - Next Generation Sequencing (NGS)
Whole Exome Sequencing
Whole Genome Sequencing
1.) Drazkowska K, Cieslicka J, Kitowicz M, Pastucha A, Markiewicz L, Szymanek W, Goryca K, Kowalczyk T, Cysewski D, Bausch AR, Sikorski PJ (2025 Apr 9). Effective recognition of double-stranded RNA does not require activation of cellular inflammation Science Advances, 11(15), eads6498. . PMCID: 11980852.
2.) Buka K, Parteka-Tojek Z, Agarwal A, Denkiewicz M, Korsak S, Chiliński M, Banecki KH, Plewczynski D (2025 Mar 14). Improved cohesin HiChIP protocol and bioinformatic analysis for robust detection of chromatin loops and stripes Communications Biology, 8(), 437. . PMCID: 11906747.
3.) Czarnocka-Cieciura A, Brouze M, Gumińska N, Mroczek S, Gewartowska O, Krawczyk PS, Dziembowski A (2025 Jan 10). Comprehensive analysis of poly(A) tails in mouse testes and ovaries using Nanopore Direct RNA Sequencing Scientific Data, 12(), 43. . PMCID: 11724052.
4.) Nguyen NL, Pawłowska J, Zajaczkowski M, Weiner AKM, Cordier T, Grant DM, De Schepper S, Pawłowski J (2024 Nov). Taxonomic and abundance biases affect the record of marine eukaryotic plankton communities in sediment DNA archives. Molecular ecology resources, 24(8), e14014. doi: 10.1111/1755-0998.14014. PMID: 39188124.
5.) Rydzanicz M, Kuzniewska B, Magnowska M, Wójtowicz T, Stawikowska A, Hojka A, Borsuk E, Meyza K, Gewartowska O, Gruchota J, Miłek J, Wardaszka P, Chojnicka I, Kondrakiewicz L, Dymkowska D, Puścian A, Knapska E, Dziembowski A, Płoski R, Dziembowska M (2024 Sep 27). Mutation in the mitochondrial chaperone TRAP1 leads to autism with more severe symptoms in males EMBO Molecular Medicine, 16(11), 2976-3004. . PMCID: 11554806.
6.) Zalewska M, Błażejewska A, Gawor J, Adamska D, Goryca K, Szeląg M, Kalinowski P, Popowska M (2024 Jul 16). A newly identified IncY plasmid from multi-drug-resistant Escherichia coli isolated from dairy cattle feces in Poland Microbiology Spectrum, 12(8), e00877-24. . PMCID: 11302260.
7.) Zalewska M, Błażejewska A, Gawor J, Adamska D, Goryca K, Szeląg M, Kalinowski P, Popowska M (2024 Jul). The IncC and IncX1 resistance plasmids present in multi-drug resistant Escherichia coli strains isolated from poultry manure in Poland. Environmental science and pollution research international, 31(35), 47727-47741. . PMID: 39007976.
8.) Brouze M, Czarnocka-Cieciura A, Gewartowska O, Kusio-Kobiałka M, Jachacy K, Szpila M, Tarkowski B, Gruchota J, Krawczyk P, Mroczek S, Borsuk E, Dziembowski A (2024 Jun 22). TENT5-mediated polyadenylation of mRNAs encoding secreted proteins is essential for gametogenesis in mice Nature Communications, 15(), 5331. . PMCID: 11193744.
9.) Hollender M, Sałek M, Karlicki M, Karnkowska A (2024 Apr). Single-cell genomics revealed Candidatus Grellia alia sp. nov. as an endosymbiont of Eutreptiella sp. (Euglenophyceae). Protist, 175(2), 126018. doi: 10.1016/j.protis.2024.126018. PMID: 38325049.
10.) Janecki DM, Sen R, Szóstak N, Kajdasz A, Kordyś M, Plawgo K, Pandakov D, Philips A, Warkocki Z (2024 Jan 9). LINE-1 mRNA 3' end dynamics shape its biology and retrotransposition potential. Nucleic acids research, (), . pii: gkad1251. doi: 10.1093/nar/gkad1251. PMID: 38197223.
11.) Wężyk M, Berdyński M, Figarski A, Skrzypczak M, Ginalski K, Zboch M, Winkel I, Żekanowski C (2023 Nov 30). Rare A360T Mutation Alters GSK3β(Ser9) Binding in the Cytosolic Loop of Presenilin 1, Influencing β-Catenin Nuclear Localization and Pro-Death Gene Expression in Alzheimer’s Disease Case International Journal of Molecular Sciences, 24(23), 16999. . PMCID: 10707597.
12.) Mierzejewski B, Pulik Ł, Grabowska I, Sibilska A, Ciemerych MA, Łęgosz P, Brzoska E (2023 Nov). Coding and noncoding RNA profile of human heterotopic ossifications - Risk factors and biomarkers. Bone, 176(), 116883. doi: 10.1016/j.bone.2023.116883. PMID: 37597797.
13.) Wicik Z, Czajka P, Eyileten C, Fitas A, Wolska M, Jakubik D, von Lewinski D, Sourij H, Siller-Matula JM, Postula M (2022 Oct 3). The role of miRNAs in regulation of platelet activity and related diseases - a bioinformatic analysis. Platelets, 33(7), 1052-1064. doi: 10.1080/09537104.2022.2042233. ID: 35285386.
14.) Wróbel M, Cendrowski J, Szymańska E, Grębowicz-Maciukiewicz M, Budick-Harmelin N, Macias M, Szybińska A, Mazur M, Kolmus K, Goryca K, Dąbrowska M, Paziewska A, Mikula M, Miączyńska M (2022 Oct). Correction: ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway. Life science alliance, 5(10), . . ID: 35672146.
15.) Paszkiewicz-Kozik E, Kluska A, Piątkowska M, Bałabas A, Żeber-Lubecka N, Karczmarski J, Goryca K, Kulecka M, Wojciechowska-Lampka E, Osiadacz W, Romejko-Jarosińska J, Świerkowska M, Paziewska A, Ambrożkiewicz F, Walewski J, Mikula M, Ostrowski J (2022 Aug 29). Genetic associations with lymphomas in Polish patients: A pooled-DNA genome-wide association analysis. International journal of immunogenetics, (), . doi: 10.1111/iji.12596. ID: 36036752.
16.) Misiukiewicz-Stępien P, Mierzejewski M, Zajusz-Zubek E, Goryca K, Adamska D, Szeląg M, Krenke R, Paplińska-Goryca M (2022 Aug 15). RNA-Seq Analysis of UPM-Exposed Epithelium Co-Cultivated with Macrophages and Dendritic Cells in Obstructive Lung Diseases. International journal of molecular sciences, 23(16), . . ID: 36012391.
17.) Nowak A, Wicik Z, Wolska M, Shahzadi A, Szwed P, Jarosz-Popek J, Palatini J, Postula M, Czlonkowska A, Mirowska-Guzel D, Eyileten C (2022 Aug). The role of non-coding RNAs in neuroinflammatory process in multiple sclerosis. Molecular neurobiology, 59(8), 4651-4668. doi: 10.1007/s12035-022-02854-y. ID: 35589919.
18.) Wróbel M, Cendrowski J, Szymańska E, Grębowicz-Maciukiewicz M, Budick-Harmelin N, Macias M, Szybińska A, Mazur M, Kolmus K, Goryca K, Dąbrowska M, Paziewska A, Mikula M, Miączyńska M (2022 Jul). ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway. Life science alliance, 5(7), . . ID: 35354596.
19.) Krzyszton M, Yatusevich R, Wrona M, Sacharowski SP, Adamska D, Swiezewski S (2022 Jun 7). Single seeds exhibit transcriptional heterogeneity during secondary dormancy induction. Plant physiology, (), . . ID: 35670742.
20.) Eyileten C, Wicik Z, Keshwani D, Aziz F, Aberer F, Pferschy PN, Tripolt NJ, Sourij C, Prietl B, Prüller F, von Lewinski D, De Rosa S, Siller-Matula JM, Postula M, Sourij H (2022 May 20). Alteration of circulating platelet-related and diabetes-related microRNAs in individuals with type 2 diabetes mellitus: a stepwise hypoglycaemic clamp study. Cardiovascular diabetology, 21(1), 79. doi: 10.1186/s12933-022-01517-5. ID: 35596173.
21.) Rusetska N, Kowalski K, Zalewski K, Zięba S, Bidziński M, Goryca K, Kotowicz B, Fuksiewicz M, Kopczynski J, Bakuła-Zalewska E, Kowalik A, Kowalewska M (2022 May). CXCR4/ACKR3/CXCL12 axis in the lymphatic metastasis of vulvar squamous cell carcinoma. Journal of clinical pathology, 75(5), 324-332. . ID: 33692092.
22.) Eyileten C, Gasecka A, Nowak A, Jarosz-Popek J, Wolska M, Dizdarevic AM, Lang IM, Postula M, Ufnal M, Siller-Matula JM (2022 May). High concentration of symmetric dimethylarginine is associated with low platelet reactivity and increased bleeding risk in patients with acute coronary syndrome. Thrombosis research, 213(), 195-202. . ID: 35398728.
23.) Eyileten C, Jakubik D, Shahzadi A, Gasecka A, van der Pol E, De Rosa S, Siwik D, Gajewska M, Mirowska-Guzel D, Kurkowska-Jastrzebska I, Czlonkowska A, Postula M (2022 Apr 20). Diagnostic Performance of Circulating miRNAs and Extracellular Vesicles in Acute Ischemic Stroke. International journal of molecular sciences, 23(9), . . ID: 35562921.
24.) Czajka P, Przybyłkowski A, Nowak A, Postula M, Wolska M, Mirowska-Guzel D, Czlonkowska A, Eyileten C (2022 Feb 17). Antiplatelet drugs and liver fibrosis. Platelets, 33(2), 219-228. doi: 10.1080/09537104.2021.1883574. ID: 33577391.
25.) De Rosa S, Iaconetti C, Eyileten C, Yasuda M, Albanese M, Polimeni A, Sabatino J, Sorrentino S, Postula M, Indolfi C (2022 Jan 17). Flow-Responsive Noncoding RNAs in the Vascular System: Basic Mechanisms for the Clinician. Journal of clinical medicine, 11(2), . . ID: 35054151.
26.) Gager GM, Eyileten C, Postula M, Gasecka A, Jarosz-Popek J, Gelbenegger G, Jilma B, Lang I, Siller-Matula J (2022). Association Between the Expression of MicroRNA-125b and Survival in Patients With Acute Coronary Syndrome and Coronary Multivessel Disease. Frontiers in cardiovascular medicine, 9(), 948006. doi: 10.3389/fcvm.2022.948006. ID: 35872885.
27.) Eyileten C, Wicik Z, Simões SN, Martins-Jr DC, Klos K, Wlodarczyk W, Assinger A, Soldacki D, Chcialowski A, Siller-Matula JM, Postula M (2022 Jan). Thrombosis-related circulating miR-16-5p is associated with disease severity in patients hospitalised for COVID-19. RNA biology, 19(1), 963-979. doi: 10.1080/15476286.2022.2100629. ID: 35938548.
28.) Gager GM, von Lewinski D, Sourij H, Jilma B, Eyileten C, Filipiak K, Hülsmann M, Kubica J, Postula M, Siller-Matula JM (2021 Nov). Effects of SGLT2 Inhibitors on Ion Homeostasis and Oxidative Stress associated Mechanisms in Heart Failure. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 143(), 112169. . ID: 34560555.
29.) Kopczynski M, Rumienczyk I, Kulecka M, Statkiewicz M, Pysniak K, Sandowska-Markiewicz Z, Wojcik-Trechcinska U, Goryca K, Pyziak K, Majewska E, Masiejczyk M, Wojcik-Jaszczynska K, Rzymski T, Bomsztyk K, Ostrowski J, Mikula M (2021 Sep 22). Selective Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibition by the SCH772984 Compound Attenuates In Vitro and In Vivo Inflammatory Responses and Prolongs Survival in Murine Sepsis Models. International journal of molecular sciences, 22(19), . . ID: 34638546.
30.) Bujko M, Zalewski K, Szczyrek M, Kowalik A, Boresowicz J, Długosz A, Goryca K, Góźdź S, Kowalewska M (2021 Sep 17). Circulating Hsa-miR-431-5p as Potential Biomarker for Squamous Cell Vulvar Carcinoma and Its Premalignant Lesions. Diagnostics (Basel, Switzerland), 11(9), . . ID: 34574047.
31.) Eyileten C, Fitas A, Jakubik D, Czajka P, Mróz A, Czajkowska A, Witek K, Bakalarski W, De Rosa S, Postuła M, Małek ŁA (2021 Jul 6). Alterations in Circulating MicroRNAs and the Relation of MicroRNAs to Maximal Oxygen Consumption and Intima-Media Thickness in Ultra-Marathon Runners. International journal of environmental research and public health, 18(14), . . ID: 34299680.
32.) Rzepa Ł, Peller M, Eyileten C, Rosiak M, Kondracka A, Mirowska-Guzel D, Opolski G, Filipiak KJ, Postuła M, Kapłon-Cieslicka A (2021 Jul). Resistin is Associated with Inflammation and Renal Function, but not with Insulin Resistance in Type 2 Diabetes. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 53(7), 478-484. doi: 10.1055/a-1492-3077. ID: 34169498.
33.) Szwed P, Gąsecka A, Zawadka M, Eyileten C, Postuła M, Mazurek T, Szarpak Ł, Filipiak KJ (2021 Jun 8). Infections as Novel Risk Factors of Atherosclerotic Cardiovascular Diseases: Pathophysiological Links and Therapeutic Implications. Journal of clinical medicine, 10(12), . . ID: 34201137.
34.) Skubisz K, Januszkiewicz-Caulier J, Cybula P, Bakuła-Zalewska E, Goryca K, Paziewska A, Ambrożkiewicz F, Woliński K, Mikula M, Ostrowski J, Dedecjus M (2021 May 25). Higher EU-TIRADS-Score Correlated with BRAF V600E Positivity in the Early Stage of Papillary Thyroid Carcinoma. Journal of clinical medicine, 10(11), . . ID: 34070605.
35.) Hennig EE, Kluska A, Piątkowska M, Kulecka M, Bałabas A, Zeber-Lubecka N, Goryca K, Ambrożkiewicz F, Karczmarski J, Olesiński T, Zyskowski Ł, Ostrowski J (2021 May 25). GWAS Links New Variant in Long Non-Coding RNA <i>LINC02006</i> with Colorectal Cancer Susceptibility. Biology, 10(6), . . ID: 34070617.
36.) Gąsecka A, Banaszkiewicz M, Nieuwland R, van der Pol E, Hajji N, Mutwil H, Rogula S, Rutkowska W, Pluta K, Eyileten C, Postuła M, Darocha S, Huczek Z, Opolski G, Filipiak KJ, Torbicki A, Kurzyna M (2021 Mar 2). Prostacyclin Analogues Inhibit Platelet Reactivity, Extracellular Vesicle Release and Thrombus Formation in Patients with Pulmonary Arterial Hypertension. Journal of clinical medicine, 10(5), . . ID: 33801460.
37.) Jakubik D, Fitas A, Eyileten C, Jarosz-Popek J, Nowak A, Czajka P, Wicik Z, Sourij H, Siller-Matula JM, De Rosa S, Postula M (2021 Feb 27). MicroRNAs and long non-coding RNAs in the pathophysiological processes of diabetic cardiomyopathy: emerging biomarkers and potential therapeutics. Cardiovascular diabetology, 20(1), 55. doi: 10.1186/s12933-021-01245-2. ID: 33639953.
38.) Kolmus K, Erdenebat P, Szymańska E, Stewig B, Goryca K, Derezińska-Wołek E, Szumera-Ciećkiewicz A, Brewińska-Olchowik M, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miączyńska M (2021 Jan 8). Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses. Journal of cell science, 134(1), . . ID: 33419951.
39.) Czajka P, Fitas A, Jakubik D, Eyileten C, Gasecka A, Wicik Z, Siller-Matula JM, Filipiak KJ, Postula M (2021). MicroRNA as Potential Biomarkers of Platelet Function on Antiplatelet Therapy: A Review. Frontiers in physiology, 12(), 652579. doi: 10.3389/fphys.2021.652579. ID: 33935804.
40.) Proboszcz M, Goryca K, Nejman-Gryz P, Przybyłowski T, Górska K, Krenke R, Paplińska-Goryca M (2021). Phenotypic Variations of Mild-to-Moderate Obstructive Pulmonary Diseases According to Airway Inflammation and Clinical Features. Journal of inflammation research, 14(), 2793-2806. doi: 10.2147/JIR.S309844. ID: 34234506.
41.) Gager GM, Gelbenegger G, Jilma B, von Lewinski D, Sourij H, Eyileten C, Filipiak K, Postula M, Siller-Matula JM (2021). Cardiovascular Outcome in Patients Treated With SGLT2 Inhibitors for Heart Failure: A Meta-Analysis. Frontiers in cardiovascular medicine, 8(), 691907. doi: 10.3389/fcvm.2021.691907. ID: 34336954.
42.) Gąsecka A, Szwed P, Jasińska K, Fidali O, Kłębukowska A, Eyileten C, Postula M, Szarpak Ł, Mazurek T, Opolski G, Filipiak KJ, Ufnal M (2021). Symmetric Dimethylarginine is Altered in Patients After Myocardial Infarction and Predicts Adverse Outcomes. Journal of inflammation research, 14(), 3797-3808. doi: 10.2147/JIR.S316078. ID: 34408463.
43.) Eyileten C, Jarosz-Popek J, Jakubik D, Gasecka A, Wolska M, Ufnal M, Postula M, Toma A, Lang IM, Siller-Matula JM (2021). Plasma Trimethylamine-N-Oxide Is an Independent Predictor of Long-Term Cardiovascular Mortality in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndrome. Frontiers in cardiovascular medicine, 8(), 728724. doi: 10.3389/fcvm.2021.728724. ID: 34778397.
44.) Eyileten C, Wicik Z, Fitas A, Marszalek M, Simon JE, De Rosa S, Wiecha S, Palatini J, Postula M, Malek LA (2021). Altered Circulating MicroRNA Profiles After Endurance Training: A Cohort Study of Ultramarathon Runners. Frontiers in physiology, 12(), 792931. doi: 10.3389/fphys.2021.792931. ID: 35145424.
45.) Fatalska A, Rusetska N, Bakuła-Zalewska E, Kowalik A, Zięba S, Wroblewska A, Zalewski K, Goryca K, Domański D, Kowalewska M (2020 Dec 23). Inflammatory Proteins HMGA2 and PRTN3 as Drivers of Vulvar Squamous Cell Carcinoma Progression. Cancers, 13(1), . . ID: 33374674.
46.) Paziewska A, Polkowski M, Goryca K, Karczmarski J, Wiechowska-Kozlowska A, Dabrowska M, Mikula M, Ostrowski J (2020 Aug). Mutational Mosaics of Cell-Free DNA from Pancreatic Cyst Fluids. Digestive diseases and sciences, 65(8), 2294-2301. doi: 10.1007/s10620-019-06043-1. ID: 31925676.
47.) Szymańska E, Nowak P, Kolmus K, Cybulska M, Goryca K, Derezińska-Wołek E, Szumera-Ciećkiewicz A, Brewińska-Olchowik M, Grochowska A, Piwocka K, Prochorec-Sobieszek M, Mikula M, Miączyńska M (2020 Feb 7). Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer. EMBO molecular medicine, 12(2), e10812. doi: 10.15252/emmm.201910812. ID: 31930723.
48.) Zajdel M, Rymkiewicz G, Sromek M, Cieslikowska M, Swoboda P, Kulinczak M, Goryca K, Bystydzienski Z, Blachnio K, Ostrowska B, Borysiuk A, Druzd-Sitek A, Walewski J, Chechlinska M, Siwicki JK (2019 Oct 25). Tumor and Cerebrospinal Fluid microRNAs in Primary Central Nervous System Lymphomas. Cancers, 11(11), . . ID: 31731456.
49.) Paplińska-Goryca M, Goryca K, Misiukiewicz-Stępień P, Nejman-Gryz P, Proboszcz M, Górska K, Maskey-Warzęchowska M, Krenke R (2019 Sep). mRNA expression profile of bronchoalveolar lavage fluid cells from patients with idiopathic pulmonary fibrosis and sarcoidosis. European journal of clinical investigation, 49(9), e13153. doi: 10.1111/eci.13153. ID: 31246273.
50.) Hennig EE, Piątkowska M, Goryca K, Pośpiech E, Paziewska A, Karczmarski J, Kluska A, Brewczyńska E, Ostrowski J (2019 Jul 24). Non-<i>CYP2D6</i> Variants Selected by a GWAS Improve the Prediction of Impaired Tamoxifen Metabolism in Patients with Breast Cancer. Journal of clinical medicine, 8(8), . . ID: 31344832.
51.) Ostrowski J, Goryca K, Lazowska I, Rogowska A, Paziewska A, Dabrowska M, Ambrozkiewicz F, Karczmarski J, Balabas A, Kluska A, Piatkowska M, Zeber-Lubecka N, Kulecka M, Habior A, Mikula M (2019 May 10). Common functional alterations identified in blood transcriptome of autoimmune cholestatic liver and inflammatory bowel diseases. Scientific reports, 9(1), 7190. doi: 10.1038/s41598-019-43699-1. ID: 31076612.
52.) Karczmarski J, Goryca K, Pachlewski J, Dabrowska M, Pysniak K, Paziewska A, Kulecka M, Lenarcik M, Mroz A, Mikula M, Ostrowski J (2019). Mutation Profiling of Premalignant Colorectal Neoplasia. Gastroenterology research and practice, 2019(), 2542640. doi: 10.1155/2019/2542640. ID: 31781186.
53.) Warkocki Z, Krawczyk PS, Adamska D, Bijata K, Garcia-Perez JL, Dziembowski A (2018 Sep 6). Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. Cell, 174(6), 1537-1548.e29. . ID: 30122351.
54.) Szczesny RJ, Kowalska K, Klosowska-Kosicka K, Chlebowski A, Owczarek EP, Warkocki Z, Kulinski TM, Adamska D, Affek K, Jedroszkowiak A, Kotrys AV, Tomecki R, Krawczyk PS, Borowski LS, Dziembowski A (2018). Versatile approach for functional analysis of human proteins and efficient stable cell line generation using FLP-mediated recombination system. PloS one, 13(3), e0194887. doi: 10.1371/journal.pone.0194887. ID: 29590189.
55.) Cybulska M, Olesinski T, Goryca K, Paczkowska K, Statkiewicz M, Kopczynski M, Grochowska A, Unrug-Bielawska K, Tyl-Bielicka A, Gajewska M, Mroz A, Dabrowska M, Karczmarski J, Paziewska A, Zając L, Bednarczyk M, Mikula M, Ostrowski J (2018). Challenges in Stratifying the Molecular Variability of Patient-Derived Colon Tumor Xenografts. BioMed research international, 2018(), 2954208. doi: 10.1155/2018/2954208. ID: 30662905.
56.) Uhrynowski W, Decewicz P, Dziewit L, Radlinska M, Krawczyk PS, Lipinski L, Adamska D, Drewniak L (2017). Analysis of the Genome and Mobilome of a Dissimilatory Arsenate Reducing <i>Aeromonas</i> sp. O23A Reveals Multiple Mechanisms for Heavy Metal Resistance and Metabolism. Frontiers in microbiology, 8(), 936. doi: 10.3389/fmicb.2017.00936. ID: 28611742.
57.) Drewniak L, Krawczyk PS, Mielnicki S, Adamska D, Sobczak A, Lipinski L, Burec-Drewniak W, Sklodowska A (2016). Physiological and Metagenomic Analyses of Microbial Mats Involved in Self-Purification of Mine Waters Contaminated with Heavy Metals. Frontiers in microbiology, 7(), 1252. doi: 10.3389/fmicb.2016.01252. ID: 27559332.
58.) Szczepińska T, Kalisiak K, Tomecki R, Labno A, Borowski LS, Kulinski TM, Adamska D, Kosinska J, Dziembowski A (2015 Nov). DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts. Genome research, 25(11), 1622-33. . ID: 26294688.
59.) Volinia S, Nuovo G, Drusco A, Costinean S, Abujarour R, Desponts C, Garofalo M, Baffa R, Aeqilan R, Maharry K, Sana ME, Di Leva G, Gasparini P, Dama P, Marchesini J, Galasso M, Manfrini M, Zerbinati C, Corrà F, Wise T, Wojcik SE, Previati M, Pichiorri F, Zanesi N, Alder H, Palatini J, Huebner KF, Shapiro CL, Negrini M, Vecchione A, Rosenberg AL, Croce CM, Garzon R (2014 Dec). Pluripotent stem cell miRNAs and metastasis in invasive breast cancer. Journal of the National Cancer Institute, 106(12), . . ID: 25306216.
60.) Nakanishi H, Taccioli C, Palatini J, Fernandez-Cymering C, Cui R, Kim T, Volinia S, Croce CM (2014 Feb 6). Loss of miR-125b-1 contributes to head and neck cancer development by dysregulating TACSTD2 and MAPK pathway. Oncogene, 33(6), 702-12. . ID: 23416980.
61.) Galasso M, Dama P, Previati M, Sandhu S, Palatini J, Coppola V, Warner S, Sana ME, Zanella R, Abujarour R, Desponts C, Teitell MA, Garzon R, Calin G, Croce CM, Volinia S (2014). A large scale expression study associates uc.283-plus lncRNA with pluripotent stem cells and human glioma. Genome medicine, 6(10), 76. doi: 10.1186/s13073-014-0076-4. ID: 25352916.
62.) Previati M, Manfrini M, Galasso M, Zerbinati C, Palatini J, Gasparini P, Volinia S (2013 Oct 1). Next generation analysis of breast cancer genomes for precision medicine. Cancer letters, 339(1), 1-7. . ID: 23879964.
63.) Fassan M, Volinia S, Palatini J, Pizzi M, Fernandez-Cymering C, Balistreri M, Realdon S, Battaglia G, Souza R, Odze RD, Zaninotto G, Croce CM, Rugge Md Facg M (2013 May 16). MicroRNA Expression Profiling in the Histological Subtypes of Barrett Clinical and translational gastroenterology, 4(), e34. . ID: 23677165.
64.) Meng W, McElroy JP, Volinia S, Palatini J, Warner S, Ayers LW, Palanichamy K, Chakravarti A, Lautenschlaeger T (2013). Comparison of microRNA deep sequencing of matched formalin-fixed paraffin-embedded and fresh frozen cancer tissues. PloS one, 8(5), e64393. doi: 10.1371/journal.pone.0064393. ID: 23696889.
65.) Jones KB, Salah Z, Del Mare S, Galasso M, Gaudio E, Nuovo GJ, Lovat F, LeBlanc K, Palatini J, Randall RL, Volinia S, Stein GS, Croce CM, Lian JB, Aqeilan RI (2012 Apr 1). miRNA signatures associate with pathogenesis and progression of osteosarcoma. Cancer research, 72(7), 1865-77. . ID: 22350417.
66.) Volinia S, Galasso M, Sana ME, Wise TF, Palatini J, Huebner K, Croce CM (2012 Feb 21). Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA. Proceedings of the National Academy of Sciences of the United States of America, 109(8), 3024-9. . ID: 22315424.
67.) Lenze D, Leoncini L, Hummel M, Volinia S, Liu CG, Amato T, De Falco G, Githanga J, Horn H, Nyagol J, Ott G, Palatini J, Pfreundschuh M, Rogena E, Rosenwald A, Siebert R, Croce CM, Stein H (2011 Dec). The different epidemiologic subtypes of Burkitt lymphoma share a homogenous micro RNA profile distinct from diffuse large B-cell lymphoma. Leukemia, 25(12), 1869-1876. doi: 10.1038/leu.2011.156. ID: 21701491.
68.) Fassan M, Volinia S, Palatini J, Pizzi M, Baffa R, De Bernard M, Battaglia G, Parente P, Croce CM, Zaninotto G, Ancona E, Rugge M (2011 Oct 1). MicroRNA expression profiling in human Barrett International journal of cancer, 129(7), 1661-70. doi: 10.1002/ijc.25823. ID: 21128279.
69.) Goparaju CM, Blasberg JD, Volinia S, Palatini J, Ivanov S, Donington JS, Croce C, Carbone M, Yang H, Pass HI (2011 Jun 16). Onconase mediated NFKβ downregulation in malignant pleural mesothelioma. Oncogene, 30(24), 2767-77. . ID: 21317924.
70.) Kim T, Veronese A, Pichiorri F, Lee TJ, Jeon YJ, Volinia S, Pineau P, Marchio A, Palatini J, Suh SS, Alder H, Liu CG, Dejean A, Croce CM (2011 May 9). p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2. The Journal of experimental medicine, 208(5), 875-83. . ID: 21518799.
71.) Sana ME, Iascone M, Marchetti D, Palatini J, Galasso M, Volinia S (2011 Jan 1). GAMES identifies and annotates mutations in next-generation sequencing projects. Bioinformatics (Oxford, England), 27(1), 9-13. . ID: 20971986.
72.) Volinia S, Galasso M, Costinean S, Tagliavini L, Gamberoni G, Drusco A, Marchesini J, Mascellani N, Sana ME, Abu Jarour R, Desponts C, Teitell M, Baffa R, Aqeilan R, Iorio MV, Taccioli C, Garzon R, Di Leva G, Fabbri M, Catozzi M, Previati M, Ambs S, Palumbo T, Garofalo M, Veronese A, Bottoni A, Gasparini P, Harris CC, Visone R, Pekarsky Y, de la Chapelle A, Bloomston M, Dillhoff M, Rassenti LZ, Kipps TJ, Huebner K, Pichiorri F, Lenze D, Cairo S, Buendia MA, Pineau P, Dejean A, Zanesi N, Rossi S, (2010 May). Reprogramming of miRNA networks in cancer and leukemia. Genome research, 20(5), 589-99. . ID: 20439436.
73.) Godlewski J, Nowicki MO, Bronisz A, Nuovo G, Palatini J, De Lay M, Van Brocklyn J, Ostrowski MC, Chiocca EA, Lawler SE (2010 Mar 12). MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. Molecular cell, 37(5), 620-32. . ID: 20227367.
74.) Visone R, Rassenti LZ, Veronese A, Taccioli C, Costinean S, Aguda BD, Volinia S, Ferracin M, Palatini J, Balatti V, Alder H, Negrini M, Kipps TJ, Croce CM (2009 Oct 29). Karyotype-specific microRNA signature in chronic lymphocytic leukemia. Blood, 114(18), 3872-9. . ID: 19717645.
75.) Volinia S, Mascellani N, Marchesini J, Veronese A, Ormondroyd E, Alder H, Palatini J, Negrini M, Croce CM (2008). Genome wide identification of recessive cancer genes by combinatorial mutation analysis. PloS one, 3(10), e3380. doi: 10.1371/journal.pone.0003380. ID: 18846217.
76.) Morrison C, Palatini J, Riggenbach J, Radmacher M, Porcu P (2006 Oct 25). Fine-needle aspiration biopsy of non-Hodgkin lymphoma for use in expression microarray analysis. Cancer, 108(5), 311-8. . ID: 16944538.
Genomics Core Facility is a highly specialized laboratory dedicated to analysis of RNA and DNA sequence, structure and interactions in biological and biochemical processes.
We specialize in Genomics and its all related disciplines, such as Metagenomics, Transcriptomics, Epigenomics, Interactomics, Oncogenomics, Structural Genomics and many other dynamically developing fields.
Our lab is equipped with the most up-to-date infrastructure, including NovaSeq 6000, NextSeq 500 and MiSeq next generation sequencing systems and a wide spectrum of highly specialized instruments for fractionation, quality and quantity assessment.
You can come to us at any stage of your experiment! Our services include consultation and assistance by experienced personnel. We perform preparation of libraries from DNA (WGS, WES, Amp-seq, ATAC-Seq, ChIP-seq etc.) and RNA(different fractions: mRNA-seq ,3’ mRNA-seq, total RNA-seq, miRNA-seq, RIP-seq etc.), sequencing of custom libraries and we can conduct bioinformatic analysis of your data.
