University of Zagreb
Sinisa Skokic
Salata 11
Zagreb 10000
http://www.hiim.unizg.hr/index.php/institut/glowlab
RRID: RRID:SCR_022701
Bruker BioSpec 70/20 USR Magnetic Resonance Imager
Perkin Elmer IVIS Spectrum in vivo optical imager
Behavioral Assessment
Cell Culture
Cell Imaging
Consultation
Cryostat Histology
Data Analysis
Data Analysis And Interpretation
Data Processing
Data Processing And Interpretation
Data Visualization
Histology
Home Cage Behavioral Analysis
In-vivo Imaging
Magnetic Resonance Imaging (MRI)
Optical Imaging
Spectroscopy
Surgical Services
Training
1.) Ister R, Sternak M, Škokić S, Gajović S (2024 Mar 26). suMRak: a multi-tool solution for preclinical brain MRI data analysis Frontiers in Neuroinformatics, 18(), 1358917. . PMCID: 11002116.
2.) Ratko M, Habek N, Dobrivojević Radmilović M, Škokić S, Justić H, Barić A, Dugandžić A (2022 Jul). Role of uroguanylin The European journal of neuroscience, 56(1), 3720-3737. doi: 10.1111/ejn.15674. ID: 35445449.
3.) Justić H, Barić A, Šimunić I, Radmilović M, Ister R, Škokić S, Dobrivojević Radmilović M (2022 Jun 24). Redefining the Koizumi model of mouse cerebral ischemia: A comparative longitudinal study of cerebral and retinal ischemia in the Koizumi and Longa middle cerebral artery occlusion models. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, (), 271678X221109873. doi: 10.1177/0271678X221109873. ID: 35748043.
4.) Skukan L, Brezak M, Ister R, Klimaschewski L, Vojta A, Zoldoš V, Gajović S (2022 Feb). Lentivirus- or AAV-mediated gene therapy interventions in ischemic stroke: A systematic review of preclinical <i>in vivo</i> studies. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 42(2), 219-236. doi: 10.1177/0271678X211039997. ID: 34427147.
5.) Šećerović A, Pušić M, Kostešić P, Vučković M, Vukojević R, Škokić S, Sasi B, Vukasović Barišić A, Hudetz D, Vnuk D, Matičić D, Urlić I, Mumme M, Martin I, Ivković A (2021 Jul). Nasal Chondrocyte-Based Engineered Grafts for the Repair of Articular Cartilage "Kissing" Lesions: A Pilot Large-Animal Study. The American journal of sports medicine, 49(8), 2187-2198. doi: 10.1177/03635465211014190. ID: 34048271.
6.) Barić A, Dobrivojević Radmilović M (2021 Apr 1). Microglia and bradykinin cross talk in poststroke cognitive impairment in diabetes. American journal of physiology. Cell physiology, 320(4), C613-C618. doi: 10.1152/ajpcell.00402.2020. ID: 33502951.
7.) Romanelli P, Bieler L, Heimel P, Škokić S, Jakubecova D, Kreutzer C, Zaunmair P, Smolčić T, Benedetti B, Rohde E, Gimona M, Hercher D, Dobrivojević Radmilović M, Couillard-Despres S (2021). Enhancing Functional Recovery Through Intralesional Application of Extracellular Vesicles in a Rat Model of Traumatic Spinal Cord Injury. Frontiers in cellular neuroscience, 15(), 795008. doi: 10.3389/fncel.2021.795008. ID: 35046776.
8.) Habek N, Dobrivojević Radmilović M, Kordić M, Ilić K, Grgić S, Farkaš V, Bagarić R, Škokić S, Švarc A, Dugandžić A (2020 Mar). Activation of brown adipose tissue in diet-induced thermogenesis is GC-C dependent. Pflugers Archiv : European journal of physiology, 472(3), 405-417. doi: 10.1007/s00424-020-02347-8. ID: 31940065.
9.) Kozina N, Mihaljević Z, Lončar MB, Mihalj M, Mišir M, Radmilović MD, Justić H, Gajović S, Šešelja K, Bazina I, Horvatić A, Matić A, Bijelić N, Rođak E, Jukić I, Drenjančević I (2019 Oct 19). Impact of High Salt Diet on Cerebral Vascular Function and Stroke in <i>Tff3</i><sup>-/-</sup><i>/</i>C57BL/6N Knockout and WT (C57BL/6N) Control Mice. International journal of molecular sciences, 20(20), . . ID: 31635131.
10.) Minassian A, Dobrivojevic Radmilovic M, Vogel S, Diedenhofen M, Nelles M, Stoeber M, Wiedermann D, Hoehn M (2019 May 2). Cortical tissue loss and major structural reorganization as result of distal middle cerebral artery occlusion in the chronic phase of nude mice. Scientific reports, 9(1), 6823. doi: 10.1038/s41598-019-43341-0. ID: 31048718.
11.) Pongrac IM, Radmilović MD, Ahmed LB, Mlinarić H, Regul J, Škokić S, Babič M, Horák D, Hoehn M, Gajović S (2019 May). D-mannose-Coating of Maghemite Nanoparticles Improved Labeling of Neural Stem Cells and Allowed Their Visualization by <i>ex vivo</i> MRI after Transplantation in the Mouse Brain. Cell transplantation, 28(5), 553-567. doi: 10.1177/0963689719834304. ID: 31293167.
12.) Gorup D, Škokić S, Kriz J, Gajović S (2019 Feb 26). Tlr2 Deficiency is Associated with Enhanced Elements of Neuronal Repair and Caspase 3 Activation Following Brain Ischemia. Scientific reports, 9(1), 2821. doi: 10.1038/s41598-019-39541-3. ID: 30808918.
Laboratory for Regenerative Neuroscience / GlowLab is a multimodal preclinical in vivo imaging facility for small laboratory animals such as mice and rats. Our strongest expertise is in brain research, however it is possible to provide imaging services on any part of or on the entire animal.
The key instruments in the facility are the magnetic resonance imager (Bruker BioSpec 70/20 USR) and the optical bioluminescence/fluorescence imager (Perkin Elmer IVIS Spectrum), fully equipped with anesthesia delivery and physiological monitoring/control system.
The imaging unit of GlowLab is complemented by a cell culture laboratory and a small animal surgery room, allowing to set up and perform entire experimental protocols as needed.
The facility can provide longitudinal imaging services owing to the animal housing unit within the same space, equipped with individually ventilated cages for both rats and mice (Tecniplast Green line and Emmerald line). Home-cage monitoring is also possible for mice as an additional service with our Tecniplast DVC cages.
