Cincinnati Children's Hospital Medical Center

Contact Info:

Kenneth Setchell

3333 Burnet Avenue

Cincinnati, OH 45229-3026

https://www.cincinnatichildrens.org/service/p/pathology/mass-spectrometry

Grants and Identifiers:

RRID: RRID:SCR_022638

Instrumentation:

Services Provided:

Relevant Publications:

1.) Durumutla HB, Prabakaran AD, El Abdellaoui Soussi F, Akinborewa O, Latimer H, McFarland K, Piczer K, Werbrich C, Jain MK, Haldar SM, Quattrocelli M (2024 Nov 22). Glucocorticoid chronopharmacology promotes glucose metabolism in heart through a cardiomyocyte-autonomous transactivation program. JCI insight, 9(22), . . PMCID: 11601906.

2.) Durumutla HB, Prabakaran AD, Soussi FEA, Akinborewa O, Latimer H, McFarland K, Piczer K, Werbrich C, Jain MK, Haldar SM, Quattrocelli M (2024 Sep 11). Glucocorticoid chrono-pharmacology unveils novel targets for the cardiomyocyte-specific GR-KLF15 axis in cardiac glucose metabolism. bioRxiv : the preprint server for biology, (), . . PMCID: 10769285.

Description:

The facility is an analytical laboratory occupying ~6000 sq ft. Our lab utilizes HPLC, FAB-MS, GC-MS, LC-MS/MS, and LC-HRMS for screening and quantification of metabolites and drugs, development of targeted assays, and for biomarker discovery using metabolomics and lipidomics analysis