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Informatics Services 4 Research

Cincinnati Children's Hospital Medical Center

Contact Info:

Ron Bryson

3333 Burnet Avenue

Cincinnati, OH 45229-3026

https://www.cincinnatichildrens.org/research/divisions/b/bmi/resource-service

Grants and Identifiers:

RRID: RRID:SCR_022622

Instrumentation:

Services Provided:

Relevant Publications:

1.) Caldwell JT, Shi T, Burg AR, Koby A, Roskin KM, Peters AL, DePasquale EA, Woodle ES, Hildeman DA (2025 Oct 24). CO-STIMULATORY BLOCKADE PREVENTS INTRAGRAFT ACCRUAL OF CLASS-SWITCHED, ACTIVATED B CELLS DESPITE FAILING TO PREVENT T-CELL MEDIATED REJECTION bioRxiv, (), 2025.10.24.683156. . PMCID: 12633403.


2.) Han SJY, Adani V, Farrow E, Parma B, Chang CF, Cochran K, Ramkissoon PJK, Esteban E, Elliott KH, Peterson KA, Gebelein BA, Garcia-Castro MI, Brugmann SA (2025 Aug 31). A dual role for GLI3 signaling in neural crest development. bioRxiv : the preprint server for biology, (), . . PMID: 40909740.


3.) Shook MS, Lu X, Chen X, Edsall LE, Granitto M, Virolainen SJ, Forney C, Donmez OA, Parameswaran S, Fadden C, Dexheimer PJ, Jenkins S, Grashel B, Kaufman KM, Hershey GK, Martin LJ, Satish L, Weirauch MT, Kottyan LC (2025 Aug 20). Massively parallel analysis of genotype-dependent enhancer activity among atopic dermatitis genetic risk variants. The Journal of allergy and clinical immunology, (), . pii: S0091-6749(25)00862-0. doi: 10.1016/j.jaci.2025.07.032. PMID: 40846081.


4.) Shi M, Crouse B, Sundaram N, Pode Shakked N, Thorner K, King NM, Dutta P, Ester L, Zhang W, Govindarajah V, Kopan R, Cebrian C, Mayhew CN, Helmrath MA, Bonventre JV, McCracken KW (2025 Jul 3). Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud. Cell stem cell, 32(7), 1055-1070.e8. . PMID: 40345193.


5.) Lee S, Ren L, Li W, Paranjpe A, Zhou P, Potter A, Huppert SS, Shin S (2025 Jul 1). Rbpj deletion in hepatic progenitor cells attenuates endothelial responses and fibrosis in DDC-fed mice. Hepatology communications, 9(7), . . PMID: 40536537.


6.) Sinton JW, Marcum S, Duan Q, Geisler K, Cooper D, Ding L, Meinzen-Derr J, Wiley S, McAuliffe J (2024 Dec 10). Prospective Observational Study of Sympathetic Failure as a Mechanism Associated with Bradycardia During Induction of General Anesthesia in Children with Down Syndrome The journal of pediatric research, 11(4), 241-249. . PMCID: 12080589.


7.) Shi M, Crouse B, Sundaram N, Pode Shakked N, Ester L, Zhang W, Janakiram V, Kopan R, Helmrath MA, Bonventre JV, McCracken KW (2024 Sep 20). Integrating collecting systems in kidney organoids through fusion of distal nephron to ureteric bud bioRxiv, (), 2024.09.19.613645. . PMCID: 11429897.


8.) Sheth M, Sharma M, Lehn M, Reza H, Takebe T, Takiar V, Wise-Draper T, Esfandiari L (2024 Sep). Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids. APL bioengineering, 8(3), 036106. . PMID: 39092008.


9.) Sayeed K, Parameswaran S, Beucler MJ, Edsall LE, VonHandorf A, Crowther A, Donmez O, Hass M, Richards S, Forney C, Wright J, Leong MML, Murray-Nerger LA, Gewurz BE, Kaufman KM, Harley JB, Zhao B, Miller WE, Kottyan LC, Weirauch MT (2024 May 22). Human cytomegalovirus infection coopts chromatin organization to diminish TEAD1 transcription factor activity. bioRxiv : the preprint server for biology, (), . . PMID: 38645179.


10.) Xu N, Alfieri CM, Yu Y, Guo M, Yutzey KE (2024 Apr 25). Wnt Signaling Inhibition Prevents Postnatal Inflammation and Disease Progression in Mouse Congenital Myxomatous Valve Disease Arteriosclerosis, thrombosis, and vascular biology, 44(7), 1540-1554. . PMCID: 11209782.


11.) Sayeed K, Parameswaran S, Beucler MJ, Edsall LE, VonHandorf A, Crowther A, Donmez O, Hass M, Richards S, Forney C, Wright J, Leong MM, Murray-Nerger LA, Gewurz BE, Kaufman KM, Harley JB, Zhao B, Miller WE, Kottyan LC, Weirauch MT (2024 Apr 13). Human cytomegalovirus extensively re-organizes the human genome, diminishing TEAD1 transcription factor activity bioRxiv, (), 2024.04.12.588762. . PMCID: 11030363.


12.) Schrenk S, Bischoff LJ, Goines J, Cai Y, Vemaraju S, Odaka Y, Good SR, Palumbo JS, Szabo S, Reynaud D, Van Raamsdonk CD, Lang RA, Boscolo E (2023 Apr 6). MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ. Nature communications, 14(1), 1929. . PMID: 37024491.


13.) Boch S, Wildeman C, Dexheimer J, Kahn R, Lambert J, Beal S (2024 Nov-Dec). Pediatric Health and System Impacts of Mass Incarceration, 2009-2020: A Matched Cohort Study. Academic pediatrics, 24(8), 1285-1295. doi: 10.1016/j.acap.2024.05.010. PMID: 38823498.


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We collaborate with researchers at the intersection of research, healthcare and technology to accelerate discovery and improve health outcomes.