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BRC Transcriptional Regulation and Expression Facility

Cornell University

Contact Info:

Jen Grenier

130 Biotechnology Building

Ithaca, NY 14850

https://www.brc.cornell.edu/

Grants and Identifiers:

RRID: RRID:SCR_022532

Instrumentation:

Services Provided:

ATAC-Seq

End-to-end Service

Genomics

RNA analysis

RNA Isolation

RNAseq

Sequencing - Next Generation Sequencing (NGS)

Relevant Publications:

1.) Yu YT, Olarte Castillo X, Reboul G, Zehr J, Sun Y, Anderson R, Wang M, Sun Q, Tallmadge R, Sams K, Brown J, Marra N, Stanhope B, Grenier J, Parrish CR, Pusterla N, Divers T, Mittel L, Goodman LB (2025 Jan 29). Genome sequence of Equine Erythroparvovirus 1, identified in the United States Microbiology Resource Announcements, 14(3), e00897-24. . PMCID: 11895488.


2.) Iu DS, Maya J, Vu LT, Fogarty EA, McNairn AJ, Ahmed F, Franconi CJ, Munn PR, Grenier JK, Hanson MR, Grimson A (2024 Dec 2). Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome Proceedings of the National Academy of Sciences of the United States of America, 121(50), e2415119121. . PMCID: 11648872.


3.) Watson NB, Patel RK, Kean C, Veazey J, Oyesola OO, Laniewski N, Grenier JK, Wang J, Tabilas C, Yee Mon KJ, McNairn AJ, Peng SA, Wesnak SP, Nzingha K, Davenport MP, Tait Wojno ED, Scheible KM, Smith NL, Grimson A, Rudd BD (2024 Feb 23). The gene regulatory basis of bystander activation in CD8(+) T cells. Science immunology, 9(92), eadf8776. doi: 10.1126/sciimmunol.adf8776. PMID: 38394230.


4.) Olarte-Castillo XA, Plimpton L, McQueary H, Sun Y, Yu YT, Cover S, Richardson AN, Jin Y, Grenier JK, Cummings KJ, Bunting E, Diuk-Wasser M, Needle D, Schuler K, Stanhope MJ, Whittaker G, Goodman LB (2023 Oct 26). Detection and characterization of novel luchacoviruses, genus Alphacoronavirus, in saliva and feces of meso-carnivores in the northeastern United States Journal of Virology, 97(11), e00829-23. . PMCID: 10688340.


5.) Olarte-Castillo XA, Plimpton L, McQueary H, Sun Y, Yu YT, Cover S, Richardson AN, Jin Y, Grenier JK, Cummings KJ, Bunting E, Diuk-Wasser M, Needle D, Schuler K, Stanhope MJ, Whittaker G, Goodman LB (2023 Sep 13). Detection and characterization of novel luchacoviruses, genus Alphacoronavirus, shed in saliva and feces of meso-carnivores in the northeastern United States bioRxiv, (), 2023.05.31.541188. . PMCID: 10515766.


6.) Sosnicki DM, Cohen R, Asano A, Nelson JL, Mukai C, Comizzoli P, Travis AJ (2023 Sep 11). Segmental differentiation of the murine epididymis: identification of segment-specific, GM1-enriched vesicles and regulation by luminal fluid factors Biology of Reproduction, 109(6), 864-877. . PMCID: 10724454.


Description:

The Transcriptional Regulation & Expression Facility offers end-to-end genomics profiling services including RNAseq, small RNA sequencing, and ATACseq.