Penn State College of Medicine
Han Chen
500 University Drive, P.O.Box 850
Room C1730
Hershey, PA 17033
https://research.med.psu.edu/core-facilities/light-microscopy/
RRID: RRID:SCR_022526
Leica SP8 FCS/ FLIM
Light Sheet Fluorescent Microscope (LSFM)
Leica SP8 STED 3X Inverted Confocal
Nikon A1 MP+ Upright Multiphoton
DeltaVisionElite Deconvolution Inverted
Image processing workstation
Confocal Microscope With FCS/FLIM Capabilities
Confocal Microscopy
Confocal/ Super Resolution Microscope
Microscopy
Multiphoton Microscopy
Super-resolution Microscopy
1.) Khatib JB, Dhoonmoon A, Moldovan GL, Nicolae CM (2024 Jul 23). PARP10 promotes the repair of nascent strand DNA gaps through RAD18 mediated translesion synthesis Nature Communications, 15(), 6197. . PMCID: 11266678.
2.) Torres MC, Rebok A, Sun D, Spratt TE (2024 Jul 1). Activity of DNA polymerase κ across the genome in human fibroblasts Proceedings of the National Academy of Sciences of the United States of America, 121(28), e2403130121. . PMCID: 11252913.
3.) Pale LM, Khatib JB, Nicolae CM, Moldovan GL (2024 Apr 20). CRISPR knockout genome-wide screens identify the HELQ-RAD52 axis in regulating the repair of cisplatin-induced single stranded DNA gaps bioRxiv, (), 2024.04.17.589988. . PMCID: 11042333.
4.) Ye Y, Liang X, Wang G, Bewley MC, Hamamoto K, Liu X, Flanagan JM, Wang HG, Takahashi Y, Tian F (2024 Mar 15). Identification of membrane curvature sensing motifs essential for VPS37A phagophore recruitment and autophagosome closure Communications Biology, 7(), 334. . PMCID: 10942982.
5.) Lambert GS, Rice BL, Kaddis Maldonado RJ, Chang J, Parent LJ (2024 Jan 18). Comparative analysis of retroviral Gag-host cell interactions: focus on the nuclear interactome bioRxiv, (), 2024.01.18.575255. . PMCID: 10827203.
6.) Kazzaz SA, Shaikh KA, White J, Zhou Q, Powell WH, Harhaj EW (2024 Jan). Phosphorylation of aryl hydrocarbon receptor interacting protein by TBK1 negatively regulates IRF7 and the type I interferon response. The Journal of biological chemistry, 300(1), 105525. . PMID: 38043800.
7.) Saha K, Subramenium Ganapathy A, Wang A, Arumugam P, Michael Morris N, Harris L, Yochum G, Koltun W, Perdew GH, Nighot M, Ma T, Nighot P (2023 Dec). Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation. Mucosal immunology, 16(6), 826-842. . PMID: 37716509.
8.) Chang J, Parent LJ (2023 Nov 22). HIV-1 Gag co-localizes with euchromatin histone marks at the nuclear periphery Journal of Virology, 97(12), e01179-23. . PMCID: 10734548.
9.) Hattori T, Fundora KA, Hamamoto K, Opozda DM, Liang X, Liu X, Zhang J, Uzun Y, Takahashi Y, Wang HG (2023 Sep 21). ER stress elicits non-canonical CASP8 (caspase 8) activation on autophagosomal membranes to induce apoptosis Autophagy, 20(2), 349-364. . PMCID: 10813646.
10.) Pandya Shesh B, Slagle-Webb B, Shenoy G, Khristov V, Zacharia BE, Connor JR (2023 Sep). Uptake of H-ferritin by Glioblastoma stem cells and its impact on their invasion capacity. Journal of cancer research and clinical oncology, 149(12), 9691-9703. doi: 10.1007/s00432-023-04864-2. PMID: 37237166.
11.) Kaddis Maldonado R, Lambert GS, Rice BL, Sudol M, Flanagan JM, Parent LJ (2023 Aug 15). The Rous sarcoma virus Gag Polyprotein Forms Biomolecular Condensates Driven by Intrinsically-disordered Regions. Journal of molecular biology, 435(16), 168182. . PMID: 37328094.
12.) Maldonado RK, Rice BL, Lambert GS, Sudol M, Flanagan JM, Parent LJ (2023 Apr 8). The Rous sarcoma virus Gag polyprotein forms biomolecular condensates driven by intrinsically-disordered regions. bioRxiv : the preprint server for biology, (), . . PMID: 37066255.
The Light Microscopy Imaging Core at Penn State College of Medicine provides consultation and training in ultra-high-resolution imaging of cells and tissues in fixed or live states. The core also provides expertise in quantitative image analysis and consultations on microscopy-related research projects.
