University of Pennsylvania

Contact Info:

Jeremy Wang

https://www.vet.upenn.edu/research/core-resources-facilities/transgenic-mouse-core

Grants and Identifiers:

RRID: RRID:SCR_022441

Instrumentation:

Services Provided:

Relevant Publications:

1.) Snitow ME, Michki SN, Chaudhry FN, Park Y, Dherwani R, Katzen JB, Frank DB, Zepp JA (2026 Jan 27). Stc1-expressing myofibroblasts are a developmentally distinct lineage cleared through apoptosis in the neonatal lung. Cell reports, 45(1), 116750. . PMCID: 12976561.

2.) Brooks DL, Carrasco MJ, Qu P, Peranteau WH, Ahrens-Nicklas RC, Musunuru K, Alameh MG, Wang X (2023 Jun 10). Rapid and definitive treatment of phenylketonuria in variant-humanized mice with corrective editing. Nature communications, 14(1), 3451. . PMID: 37301931.

Description:

Offers embryological manipulation services, focused on, but not limited to, murine model systems.  These services primarily enable generation of genetically modified murine models, as well as experimental research in germ cell function and early embryonic development.