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University of Pennsylvania Perelman School of Medicine Viral Molecular High Density Sequencing Core Facility

University of Pennsylvania

Contact Info:

Rick Bushman

https://med-upenn.corefacilities.org/service_center/5129/?tab=about

Grants and Identifiers:

RRID: RRID:SCR_022433

Instrumentation:

Services Provided:

Relevant Publications:

1.) Segura EE, Hart K, Campo Fernandez B, Brown D, Tam K, Gutierrez Garcia A, Seigneurbieux E, Li K, Mulumba C, Blakely E, Masiuk K, Sinha R, Sharma D, Everett J, Hogenauer M, Cromer MK, Bushman F, MacKenzie TC, Kohn DB (2025 Sep 17). Lentiviral vectors for hematopoietic stem cell gene therapy restore α-globin expression in α-thalassemia red blood cells Cell Reports Medicine, 6(10), 102362. . PMCID: 12629793.


Description:

Offers Illumina sequencing and bioinformatic expertise to assist researchers with gene therapy trial evaluations, viral integration profiling, CRISPR off-target analyses. Assists with bioinformatic analyses including RNAseq transcription profiling and 16S taxonomic assignments.