Harvard Medical School

Contact Info:

Gregory Heffron

Bio-NMR Core, Harvard Medical School

200 Longwood Avenue

Boston, MA 02115

https://eqnmr.med.harvard.edu

Grants and Identifiers:

RRID: RRID:SCR_022967

Instrumentation:

Other Equipment

Bruker NEO 700 NMR with TCI cryoprobe Bruker NEO 600 NMR with QCIF cryoprobe Bruker 600MHz AVANCE III NMR with TCI cryoprobe Bruker 600MHz AVANCE II NMR with HCN cryoprobe Agilent MR-400MHz NMR with One Probe SampleJet NMR autosampler Agilent AS7700 NMR autosampler Gilson NMR liquid handler 1H and 19F NMR-ready fragment libraries

Services Provided:

Fragment-based Drug Discovery

Fragment-based Screening

Metabolomics

Natural Product Analysis

NMR Medicinal Chemistry Support

NMR Quality Control For Biologic Drugs

NMR Quality Control For Biosimilars

Nuclear Magnetic Resonance (NMR)

Protein NMR

Structure Determination

Relevant Publications:

Description:

State-of-the-art resource for NMR that offers services in fragment-based screening and drug discovery, characterization and QC of biologics and biosimilar drugs, metabolomics, protein NMR, small molecule NMR, and NMR of natural products. The facility offers 400-700MHz systems, many with cryogenic probes. The staff is highly experienced and dedicated.