University of Virginia
Katia Sol-Church
Pinn Hall 1060-1074-1076
1340 Jefferson Park Avenue
Charlottesville, VA 22908
https://med.virginia.edu/gatc/
RRID: RRID:SCR_018883
Other Citation Identifiers 5P30CA044579
Illumina NextSeq 1000 and NextSeq 2000 Sequencing Systems
Benchtop sequencers that allow you to explore new science across variety of current and emerging applications, with higher efficiency and fewer restraints. [Product Link]
RRID:SCR_020140
10X Genomics Chromium Controller
Illumina MiSeq Sequencing System
Nanopore GridION
Applied Biosystems QuantStudio 6 Flex Real Time PCR System
Agilent Bioanalyzer and Tape Station
NanoVue spectrophotometer
Qubit 3.0 fluorometer
Covaris S2
Qiacuity dPCR
10x Genomics
Assay Development
CDNA Synthesis
Clinical Research
Consultations
Copy Number Variation (CNV)
Customized Protocols
Data Analysis
Data Processing And Interpretation
Digital PCR
DNA Analysis
Genomics
Genotyping
Library Services
Long Read Sequencing
Metagenomics Analysis
Microbiome
Nanopore Sequencing
Real-time qPCR
RNA analysis
RNA Integrity
RNAseq
Sequencing - Next Generation Sequencing (NGS)
Shared Instrumentation Oversight & Maintenance
Single-Cell Analysis
Single-cell Sequencing
Whole Exome Sequencing
1.) Cwiek A, Paila U, Markowska Z, Genet N, Jackson M, Genet G, Cain SR, Aragon JW, Nelson EA, Borges RM, Sutherland AE, Hirschi KK (2026 Apr 17). Retinoic acid regulates fetoplacental vascularization via notch signaling and a SEMA3E/F-PLEXIND1 axis. iScience, 29(4), . . PMCID: 13010106.
2.) Camacho LQ, Fallahi-Sichani M (2026 Feb 14). Systematic multivariate analysis of chromatin complex dependencies reveals Set1C/COMPASS as a melanoma-enriched epigenetic vulnerability. bioRxiv : the preprint server for biology, (), . . PMCID: 12918794.
3.) Nash WT, Okusa MD (2026 Jan). Neuroimmune Regulation for Acute Kidney Injury Therapy: Insights Along the Path From Bench to Bedside. Seminars in nephrology, 46(1), 151674. . PMID: 41068024.
4.) Dunham N, Wang Z, Neelamraju Y, Guo Y, Paudel BB, Meydan C, Gandara JA, Abdelmalak FA, Fan H, Hardwick J, Layer JH, Lee T, Maier B, McDonald WH, Patnaik I, Prajapati S, Rapaport F, Sheridan C, Sheynkman G, Zumbo P, Becker MW, Bullinger L, Carroll MP, D'Andrea RJ, Dillon R, Levine RL, Mason CE, Melnick AM, Neuberg DS, Bekiranov S, Zang C, Davé UP, Garrett-Bakelman FE (2025 Nov 25). The LMO2-LDB1-TAL1 complex regulates transcription networks in acute myeloid leukemia Blood Neoplasia, 3(1), 100186. . PMCID: 12835595.
5.) Daboin C, Nicklow E, Griffin DR (2025 Nov). Mechanical maturation of human dermal fibroblast-laden microporous annealed particle scaffolds during long-term in vitro culture. Acta biomaterialia, 207(), 353-363. . PMID: 41130429.
6.) Aragon JW, Nelson EA, Chavkin NW, Jackson MG, Heo W, Cain SR, Markowska Z, Bradecamp GE, Genet G, Ćwiek A, Hirschi KK (2025 Oct 28). Emergence of endothelial subtypes and role of cell cycle control in arterial-venous specification during embryonic vascular development. Cell reports, 44(10), 116368. . PMCID: 12685131.
7.) Liu Y, McDaniel JA, Chen C, Yang L, Kipcak A, Savier EL, Erisir A, Cang J, Campbell JN (2025 Oct 15). Co-Conservation of synaptic gene expression and circuitry in collicular neurons Nature Communications, 16(), 9146. . PMCID: 12528736.
8.) Barnes RW, Thakur A, Onengut-Gumuscu S, Lum LG, Dolatshahi S (2025 Oct 1). LAG3+ CD8+ T cell subset drives HR+/HER2- breast cancer reduction in bispecific antibody armed activated T cell therapy. Journal of immunology (Baltimore, Md. : 1950), 214(10), 2756-2769. . PMID: 40795300.
9.) Yadav N, Xiao A, Zhong Q, Kumar P, Konduru G, Hart W, Lazzara M, Purow B (2025 Sep). Synergistic activity of simvastatin and irinotecan chemotherapy against glioblastoma converges on TGF-β signaling. Journal of neuro-oncology, 174(3), 621-633. . PMID: 40434539.
10.) Achakkagari S, Camargo-Tavares JC, Praslickova D, Martini C, Bizimungu B, Anglin NL, Manrique-Carpintero N, Lindqvist-Kreuze H, Tai HH, Strömvik MV (2025 Sep). Better together: Subgenomes for allotetraploid potato wild relative Solanum acaule Bitt. reveal origins in Petota Clade 3 and 4. The plant genome, 18(3), e70095. . PMID: 40836401.
11.) Bartosik AR, Hou PC, Tang S, Vaughn JP, Smaldino PJ, Ratan A, Mayo MW, Wang YH (2025 Jul 2). Loss of DHX36/G4R1, a G4 resolvase, drives genome instability and regulates innate immune gene expression in cancer cells Nucleic Acids Research, 53(12), gkaf621. . PMCID: 12214017.
12.) Su Z, Tian M, Shibata E, Shibata Y, Yang T, Wang Z, Jin F, Zang C, Dutta A (2025 Jun 24). Regulation of epigenetics and chromosome structure by human ORC2. Cell reports, 44(6), 115816. . PMID: 40504688.
13.) Cwiek A, Dailey RK, Kameshwar AKS, Suzuki M, Isaac J, deRonde K, Conaway M, Bennett KM, Baldelomar EJ, Li T, Wu T, Hoch MR, Chavkin NW, Walker PD, Hirschi KK, Reidy KJ, Charlton JR (2025 May 29). Preterm birth increases susceptibility to hyperglycemia induced glomerular alterations in male mice. Scientific reports, 15(1), 18934. . PMID: 40442182.
14.) Barnes RW, Thakur A, Onengut-Gumuscu S, Lum LG, Dolatshahi S (2025 May 10). LAG3+ CD8+ T cell Subset Drives HR+/HER2− Breast Cancer Reduction in Bispecific Antibody Armed Activated T Cell Therapy bioRxiv, (), 2025.01.04.631323. . PMCID: 12248021.
15.) Tajammal A, Haddox S, Zahra S, Cornelison R, Fierti AO, Li H (2025 May 7). BLADE-R: streamlined RNA extraction for molecular diagnostics and high-throughput applications. bioRxiv : the preprint server for biology, (), . . PMID: 40196560.
16.) Zengeler KE, Hollis A, Deutsch TC, Samuels JD, Ennerfelt H, Moore KA, Steacy EJ, Sabapathy V, Sharma R, Patel MK, Lukens JR (2025 May 2). Inflammasome signaling in astrocytes modulates hippocampal plasticity Immunity, 58(6), 1519-1535.e11. . PMCID: 12158643.
17.) Phillips E, van Enk S, Kildgaard S, Schlue S, Göttmann M, Jennings V, Bethke F, Müller G, Herold-Mende C, Pastor-Flores D, Schneider M, Helm D, Ostenfeld Larsen T, Goidts V (2025 Mar). Malformin C preferentially kills glioblastoma stem-like cells via concerted induction of proteotoxic stress and autophagic flux blockade. Molecular oncology, 19(3), 785-807. . PMID: 39462997.
18.) Nicklow E, Pruett LJ, Singh N, Daniero JJ, Griffin DR (2025 Feb 14). Exploration of biomaterial-tissue integration in heterogeneous microporous annealed particle scaffolds in subcutaneous implants over 12 months Acta biomaterialia, 196(), 183-197. . PMCID: 11968225.
19.) Beshr G, Sikandar A, Gläser J, Fares M, Sommer R, Wagner S, Köhnke J, Titz A (2025 Feb). A fucose-binding superlectin from Enterobacter cloacae with high Lewis and ABO blood group antigen specificity. The Journal of biological chemistry, 301(2), 108151. . PMID: 39743000.
20.) Liu Y, McDaniel JA, Chen C, Yang L, Kipcak A, Savier EL, Erisir A, Cang J, Campbell JN (2025 Jan 23). Co-Conservation of Synaptic Gene Expression and Circuitry in Collicular Neurons bioRxiv, (), 2025.01.23.634521. . PMCID: 11785205.
21.) Fu Z, Ganesana M, Hwang P, Tan X, Kinkaid MM, Sun YY, Bian E, Weybright A, Chen HR, Sol-Church K, Eyo UB, Pridans C, Quintana FJ, Robson SC, Kumar P, Venton BJ, Schaefer A, Kuan CY (2025 Jan 22). Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39 Nature Communications, 16(), 956. . PMCID: 11754601.
22.) Garcia Diaz J, Park SJ, Legouez L, Comlekoglu T, Beck A, Kuan CY, Hahn YS (2025). Zika virus induces monocyte recruitment in the immunocompetent adult brain driving chronic inflammation. Frontiers in immunology, 16(), 1597776. . PMID: 40688087.
23.) Webster AN, Becker JJ, Li C, Schwalbe DC, Kerspern D, Karolczak EO, Bundon CB, Onoharigho RA, Crook M, Jalil M, Godschall EN, Dame EG, Dawer A, Belmont-Rausch DM, Pers TH, Lutas A, Habib N, Güler AD, Krashes MJ, Campbell JN (2024 Dec). Molecular connectomics reveals a glucagon-like peptide 1-sensitive neural circuit for satiety. Nature metabolism, 6(12), 2354-2373. . PMID: 39627618.
24.) Zhang J, Nie F, Luo F, Wang J (2024 Nov 28). Phasing nanopore genome assembly by integrating heterozygous variations and Hi-C data. Bioinformatics (Oxford, England), 40(12), . . PMID: 39602797.
25.) Mays JC, Mei S, Kogenaru M, Quysbertf HM, Bosco N, Zhao X, Bianchi JJ, Goldberg A, Kidiyoor GR, Holt LJ, Fenyö D, Davoli T (2024 Sep 29). KaryoTap Enables Aneuploidy Detection in Thousands of Single Human Cells. bioRxiv : the preprint server for biology, (), . . PMID: 39386620.
26.) Dube CJ, Zhang Y, Saha S, Lai M, Gibert MK, Escalante M, Hudson K, Wong D, Marcinkiewicz P, Yener U, Sun Y, Xu E, Sorot A, Mulcahy E, Kefas B, Hanif F, Guessous F, Vernon A, Patel MK, Schiff D, Zong H, Purow B, Holland E, Sonkusare S, Sontheimer H, Abounader R (2024 Aug 23). Microenvironment T-Type calcium channels regulate neuronal and glial processes to promote glioblastoma growth. bioRxiv : the preprint server for biology, (), . . PMID: 39229003.
27.) Kitelinger LE, Thim EA, Zipkowitz SY, Price RJ, Bullock TNJ (2024 Aug 7). Tissue- and Temporal-Dependent Dynamics of Myeloablation in Response to Gemcitabine Chemotherapy. Cells, 13(16), . . PMID: 39195207.
28.) Limerick A, McCabe EA, Turner JS, Kuang KW, Brautigan DL, Hao Y, Chu CY, Fu SH, Ahmadi S, Xu W, Fu Z (2024 Jul 26). An Epilepsy-Associated CILK1 Variant Compromises KATNIP Regulation and Impairs Primary Cilia and Hedgehog Signaling Cells, 13(15), 1258. . PMCID: 11311665.
29.) Shamsuzzaman S, Deaton RA, Salamon A, Doviak H, Serbulea V, Milosek VM, Evans MA, Karnewar S, Saibaba S, Alencar GF, Shankman LS, Walsh K, Bekiranov S, Kocher O, Krieger M, Kull B, Persson M, Michaëlsson E, Bergenhem N, Heydarkhan-Hagvall S, Owens GK (2024 Jun 17). A Novel Mouse Model of Myocardial Infarction, Plaque Rupture and Stroke Shows Improved Survival with Myeloperoxidase Inhibition Circulation, 150(9), 687-705. . PMCID: 11347105.
30.) Abebayehu D, Pfaff BN, Bingham GC, Miller AE, Kibet M, Ghatti S, Griffin DR, Barker TH (2024 Jun 14). A Thy-1-negative immunofibroblast population emerges as a key determinant of fibrotic outcomes to biomaterials. Science advances, 10(24), eadf2675. . PMID: 38875340.
31.) Chang TY, Waxman DJ (2024 Jun 12). HDI-STARR-seq: Condition-specific enhancer discovery in mouse liver in vivo. bioRxiv : the preprint server for biology, (), . . PMID: 38915578.
32.) Karnewar S, Karnewar V, Deaton RA, Shankman LS, Benavente ED, Williams CM, Bradley X, Alencar GF, Bulut GB, Kirmani S, Baylis RA, Zunder ER, den Ruijter HM, Pasterkamp G, Owens GK (2024 Jun). IL-1β Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice. Arteriosclerosis, thrombosis, and vascular biology, 44(6), 1379-1392. . PMID: 38695167.
33.) Luse MA, Dunaway LS, Nyshadham S, Carvalho A, Sedovy MW, Ruddiman CA, Tessema R, Hirschi K, Johnstone SR, Isakson BE (2024 May 31). Endothelial-adipocyte Cx43 Mediated Gap Junctions Can Regulate Adiposity Function, 5(5), zqae029. . PMCID: 11384900.
34.) Limerick A, McCabe EA, Turner JS, Kuang KW, Brautigan DL, Hao Y, Chu C, Fu SH, Ahmadi S, Xu W, Fu Z (2024 May 17). An epilepsy-associated CILK1 variant compromises KATNIP regulation and impairs primary cilia and Hedgehog signaling. bioRxiv : the preprint server for biology, (), . . PMID: 38798407.
35.) Raimer Young HM, Hou PC, Bartosik AR, Atkin ND, Wang L, Wang Z, Ratan A, Zang C, Wang YH (2024 Apr 24). DNA fragility at topologically associated domain boundaries is promoted by alternative DNA secondary structure and topoisomerase II activity. Nucleic acids research, 52(7), 3837-3855. . PMID: 38452213.
36.) Grewal S, Yang CY, Scholefield D, Ashling S, Ghosh S, Swarbreck D, Collins J, Yao E, Sen TZ, Wilson M, Yant L, King IP, King J (2024 Apr 23). Chromosome-scale genome assembly of bread wheat's wild relative Triticum timopheevii. Scientific data, 11(1), 420. . PMID: 38653999.
37.) Wetters S, Sahi V, Brosche L, Häser A, Nick P (2024 Apr 13). Monitoring Indian "Superfood" Moringa oleifera Lam. - species-specific PCR-fingerprint-based authentication for more consumer safety. NPJ science of food, 8(1), 21. . PMID: 38615055.
38.) Kupkova K, Shetty SJ, Hoffman EA, Bekiranov S, Auble DT (2024 Apr 2). Genome-scale chromatin binding dynamics of RNA Polymerase II general transcription machinery components The EMBO Journal, 43(9), 1799-1821. . PMCID: 11066129.
39.) Rodríguez NA, Patel N, Dariolli R, Ng S, Aleman AG, Gong JQX, Lin HM, Rodríguez M, Josowitz R, Sol-Church K, Gripp KW, Lin X, Song SC, Fishman GI, Sobie EA, Gelb BD (2024 Apr). HRAS-Mutant Cardiomyocyte Model of Multifocal Atrial Tachycardia. Circulation. Arrhythmia and electrophysiology, 17(4), e012022. . ID: 38415356.
40.) Tufan T, Comertpay G, Villani A, Nelson GM, Terekhova M, Kelley S, Zakharov P, Ellison RM, Shpynov O, Raymond M, Sun J, Chen Y, Bockelmann E, Stremska M, Peterson LW, Boeckaerts L, Goldman SR, Etchegaray JI, Artyomov MN, Peri F, Ravichandran KS (2024 Apr). Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release. Nature, 628(8007), 408-415. doi: 10.1038/s41586-024-07172-y. PMID: 38480883.
41.) Pujadas Liwag EM, Wei X, Acosta N, Carter LM, Yang J, Almassalha LM, Jain S, Daneshkhah A, Rao SSP, Seker-Polat F, MacQuarrie KL, Ibarra J, Agrawal V, Aiden EL, Kanemaki MT, Backman V, Adli M (2024 Mar 22). Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism. Genome biology, 25(1), 77. . PMID: 38519987.
42.) Uddin MJ, Thompson B, Leslie JL, Fishman C, Sol-Church K, Kumar P, Petri WA Jr (2024 Mar 13). Investigating the impact of antibiotic-induced dysbiosis on protection from Clostridium difficile colitis by mouse colonic innate lymphoid cells. mBio, 15(3), e0333823. . PMID: 38376154.
43.) Wang S, Riedstra CP, Zhang Y, Anandh S, Dudley AC (2024 Mar). PTEN-restoration abrogates brain colonisation and perivascular niche invasion by melanoma cells. British journal of cancer, 130(4), 555-567. . PMID: 38148377.
44.) Horitani K, Chavkin NW, Arai Y, Wang Y, Ogawa H, Yura Y, Evans MA, Cochran JD, Thel MC, Polizio AH, Sano M, Miura-Yura E, Arai Y, Doviak H, Arnold AP, Gelfand BD, Hirschi KK, Sano S, Walsh K (2024 Mar). Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure. Nature cardiovascular research, 3(3), 343-355. . PMID: 39183958.
45.) Lacinski RA, Dziadowicz SA, Stewart A, Chaharbakhshi E, Akhter H, Pisquiy JJ, Victory JH, Hardham JB, Chew C, Prorock A, Bao Y, Sol-Church K, Hobbs GR, Klein E, Nalesnik MA, Hu G, de Oliveira A, Santiago SP, Lindsey BA (2024 Feb 16). Nanosphere pharmacodynamics improves safety of immunostimulatory cytokine therapy. iScience, 27(2), 108836. . PMID: 38303687.
46.) Hart WS, Myers PJ, Purow BW, Lazzara MJ (2024 Feb 9). Divergent transcriptomic signatures from putative mesenchymal stimuli in glioblastoma cells. Cancer gene therapy, (), . doi: 10.1038/s41417-023-00724-w. PMID: 38337036.
47.) Dunaway LS, Luse MA, Nyshadham S, Bulut G, Alencar GF, Chavkin NW, Cortese-Krott M, Hirschi KK, Isakson BE (2024 Feb 1). Obesogenic diet disrupts tissue-specific mitochondrial gene signatures in the artery and capillary endothelium. Physiological genomics, 56(2), 113-127. doi: 10.1152/physiolgenomics.00109.2023. PMID: 37982169.
48.) Danoff JS, Carter CS, Gordevičius J, Milčiūtė M, Brooke RT, Connelly JJ, Perkeybile AM (2024 Feb). Maternal oxytocin treatment at birth increases epigenetic age in male offspring. Developmental psychobiology, 66(2), . . PMID: 38533486.
49.) Pourafshar S, Sharma B, Allen J, Hoang M, Lee H, Dressman H, Tyson CC, Mallawaarachchi I, Kumar P, Ma JZ, Lin PH, Scialla JJ (2024 Jan 28). Longitudinal Pilot Evaluation of the Gut Microbiota Comparing Patients With and Without Chronic Kidney Disease. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, (), . pii: S1051-2276(24)00009-8. doi: 10.1053/j.jrn.2024.01.003. PMID: 38286361.
50.) Jalil M, Coverdell TC, Gutierrez VA, Crook ME, Shi J, Stornetta DS, Schwalbe DC, Abbott SB, Campbell JN (2023 Dec 17). Molecular Disambiguation of Heart Rate Control by the Nucleus Ambiguus bioRxiv, (), 2023.12.16.571991. . PMCID: 10760142.
51.) Hasterok S, Scott TG, Roller DG, Spencer A, Dutta AB, Sathyan KM, Frigo DE, Guertin MJ, Gioeli D (2023 Dec 1). The androgen receptor does not directly regulate the transcription of DNA damage response genes Molecular cancer research : MCR, 21(12), 1329-1341. . PMCID: 11022999.
52.) Hasterok S, Scott TG, Roller DG, Spencer A, Dutta AB, Sathyan KM, Frigo DE, Guertin MJ, Gioeli D (2023 Dec 1). The Androgen Receptor Does Not Directly Regulate the Transcription of DNA Damage Response Genes. Molecular cancer research : MCR, 21(12), 1329-1341. . PMID: 37698543.
53.) Webster AN, Becker JJ, Li C, Schwalbe DC, Kerspern D, Karolczak EO, Godschall EN, Belmont-Rausch DM, Pers TH, Lutas A, Habib N, Güler AD, Krashes MJ, Campbell JN (2023 Nov 3). Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety bioRxiv, (), 2023.10.31.564990. . PMCID: 10635031.
54.) Karnewar S, Karnewar V, Deaton R, Shankman LS, Benavente ED, Williams CM, Bradley X, Alencar GF, Bulut GB, Kirmani S, Baylis RA, Zunder ER, den Ruijter HM, Pasterkamp G, Owens GK (2023 Oct 14). IL-1β inhibition partially negates the beneficial effects of diet-induced lipid lowering. bioRxiv : the preprint server for biology, (), . . PMID: 37873280.
55.) Tang Q, Godschall E, Brennan CD, Zhang Q, Abraham-Fan RJ, Williams SP, Güngül TB, Onoharigho R, Buyukaksakal A, Salinas R, Sajonia IR, Olivieri JJ, Calhan OY, Deppmann CD, Campbell JN, Podyma B, Güler AD (2023 Aug 25). Leptin receptor neurons in the dorsomedial hypothalamus input to the circadian feeding network Science Advances, 9(34), eadh9570. . PMCID: 10456850.
56.) Kupkova K, Shetty SJ, Pray-Grant MG, Grant PA, Haque R, Petri WA Jr, Auble DT (2023 Aug 11). Globally elevated levels of histone H3 lysine 9 trimethylation in early infancy are associated with poor growth trajectory in Bangladeshi children Clinical Epigenetics, 15(), 129. . PMCID: 10422758.
57.) Danoff JS, Ramos EN, Hinton TD, Perkeybile AM, Graves AJ, Quinn GC, Lightbody-Cimer AR, Gordevičius J, Milčiūtė M, Brooke RT, Carter CS, Bales KL, Erisir A, Connelly JJ (2023 Aug). Father's care uniquely influences male neurodevelopment. Proceedings of the National Academy of Sciences of the United States of America, 120(31), e2308798120. . PMID: 37487074.
58.) Kupkova K, Shetty SJ, Hoffman EA, Bekiranov S, Auble DT (2023 Jul 26). Genome-scale chromatin interaction dynamic measurements for key components of the RNA Pol II general transcription machinery bioRxiv, (), 2023.07.25.550532. . PMCID: 10402067.
59.) Null JL, Kim DJ, McCann JV, Pramoonjago P, Fox JW, Zeng J, Kumar P, Edatt L, Pecot CV, Dudley AC (2023 Jul 5). Periostin+ Stromal Cells Guide Lymphovascular Invasion by Cancer Cells. Cancer research, 83(13), 2105-2122. . PMID: 37205636.
60.) Wilson B, Su Z, Kumar P, Dutta A (2023 May 5). XRN2 suppresses aberrant entry of tRNA trailers into argonaute in humans and Arabidopsis PLOS Genetics, 19(5), e1010755. . ID: 10191329.
61.) Genet N, Genet G, Chavkin NW, Paila U, Fang JS, Vasavada HH, Goldberg JS, Acharya BR, Bhatt NS, Baker K, McDonnell SP, Huba M, Sankaranarayanan D, Ma GZM, Eichmann A, Thomas JL, Ffrench-Constant C, Hirschi KK (2023 Apr 25). Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone. Cell reports, 42(4), 112371. . PMID: 37043357.
62.) Kim DJ, Anandh S, Null JL, Przanowski P, Bhatnagar S, Kumar P, Shelton SE, Grundy EE, Chiappinelli KB, Kamm RD, Barbie DA, Dudley AC (2023 Apr 14). Priming a vascular-selective cytokine response permits CD8+ T-cell entry into tumors Nature Communications, 14(), 2122. . PMCID: 10101959.
63.) Dinda M, Fine RD, Saha S, Wang Z, Zang C, Li M, Smith JS (2023 Apr 14). Fob1-dependent condensin recruitment and loop extrusion on yeast chromosome III PLOS Genetics, 19(4), e1010705. . PMCID: 10132618.
64.) Przanowski P, Przanowska RK, Guertin MJ (2023 Mar 1). ANKLE1 cleaves mitochondrial DNA and contributes to cancer risk by promoting apoptosis resistance and metabolic dysregulation Communications Biology, 6(), 231. . ID: 9977882.
65.) Tang Q, Godschall E, Brennan CD, Zhang Q, Abraham-Fan RJ, Williams SP, Güngül TB, Onoharigho R, Buyukaksakal A, Salinas R, Olivieri JJ, Deppmann CD, Campbell JN, Podyma B, Güler AD (2023 Feb 26). A leptin-responsive hypothalamic circuit inputs to the circadian feeding network bioRxiv, (), 2023.02.24.529901. . PMCID: 9980144.
66.) Fragoso-Luna A, Romero-Bueno R, Eibl M, Ayuso C, Muñoz-Jiménez C, Benes V, Cases I, Askjaer P (2023 Jan 12). Expanded FLP toolbox for spatiotemporal protein degradation and transcriptomic profiling in Caenorhabditis elegans. Genetics, 223(1), . . PMID: 36321973.
67.) Bingham GC, Muehling LM, Li C, Huang Y, Ma SF, Abebayehu D, Noth I, Sun J, Woodfolk JA, Barker TH, Bonham CA (2023). High-dimensional comparison of monocytes and T cells in post-COVID and idiopathic pulmonary fibrosis. Frontiers in immunology, 14(), 1308594. . PMID: 38292490.
68.) San Martin R, Das P, Sanders JT, Hill AM, McCord RP (2022 Dec 29). Transcriptional profiling of Hutchinson-Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification. eLife, 11(), . . PMID: 36579892.
69.) Nakayama T, Roubroeks JAY, Veenstra GJC, Grainger RM (2022 Dec 1). Preparation of Intact Nuclei for Single-Nucleus Omics Using Frozen Cell Suspensions from Mutant Embryos of Xenopus tropicalis. Cold Spring Harbor protocols, 2022(12), 641-652. doi: 10.1101/pdb.prot107825. PMID: 35953244.
70.) Sun D, Llora Batlle O, van den Ameele J, Thomas JC, He P, Lim K, Tang W, Xu C, Meyer KB, Teichmann SA, Marioni JC, Jackson SP, Brand AH, Rawlins EL (2022 Nov 2). SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling. The EMBO journal, 41(21), e111338. . PMID: 36121125.
71.) Vogler M, Oleksy A, Schulze S, Fedorova M, Kojonazarov B, Nijjar S, Patel S, Jossi S, Sawmynaden K, Henry M, Brown R, Matthews D, Offermanns S, Worzfeld T (2022 Sep). An antagonistic monoclonal anti-Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis. The Journal of biological chemistry, 298(9), 102265. . PMID: 35850304.
72.) Sano S, Horitani K, Ogawa H, Halvardson J, Chavkin NW, Wang Y, Sano M, Mattisson J, Hata A, Danielsson M, Miura-Yura E, Zaghlool A, Evans MA, Fall T, De Hoyos HN, Sundström J, Yura Y, Kour A, Arai Y, Thel MC, Arai Y, Mychaleckyj JC, Hirschi KK, Forsberg LA, Walsh K (2022 Jul 14). Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality Science (New York, N.Y.), 377(6603), 292-297. . PMCID: 9437978.
73.) Rang FJ, de Luca KL, de Vries SS, Valdes-Quezada C, Boele E, Nguyen PD, Guerreiro I, Sato Y, Kimura H, Bakkers J, Kind J (2022 May 19). Single-cell profiling of transcriptome and histone modifications with EpiDamID. Molecular cell, 82(10), 1956-1970.e14. . PMID: 35366395.
74.) Turner AW, Hu SS, Mosquera JV, Ma WF, Hodonsky CJ, Wong D, Auguste G, Song Y, Sol-Church K, Farber E, Kundu S, Kundaje A, Lopez NG, Ma L, Ghosh SKB, Onengut-Gumuscu S, Ashley EA, Quertermous T, Finn AV, Leeper NJ, Kovacic JC, Björkgren JLM, Zang C, Miller CL (2022 May 19). Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk. Nature genetics, (), . doi: 10.1038/s41588-022-01069-0. ID: 35590109.
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The mission of the University of Virginia Genome Analysis and Technology Core (GATC) is to serve as a scientific educational resource and biotechnology hub enhancing the scope and quality of basic and translational research. The goal of the core staff is to enable Next Generation Sequencing projects for novice and experienced users, by providing education, and timely assistance in all facets of experimentation from project design and execution to data analysis and reporting. The core champions Scientific Rigor and Reproducibility at all stages of a project life cycle.
