RRID:SCR_022967 | Boston, MA 02115 | Nuclear Magnetic Resonance (NMR), Natural Product Analysis, Metabolomics, Protein NMR, Fragment-based Drug Discovery, Fragment-based Screening, NMR Quality Control For Biologic Drugs, NMR Quality Control For Biosimilars, NMR Medicinal Chemistry Support, Structure Determination | 11/14/2022 |
RRID:SCR_022950 | Boston, MA 02115 | ES Cell Technology (Mouse), Embryo Cryopreservation & Recovery Services, CRISPR Injection Services, ES Cell Electroporation, ES Cell Injection, Fresh/Frozen Sperm IVF, Injection Of DNA Constructs, Sperm Cryopreservation, Tail Biopsy | 11/07/2022 |
RRID:SCR_018270 | Boston, MA 02115 | Biolayer Interferometry (BLI), Circular Dichroism (CD), Differential Scanning Fluorimetry (DSF), Isothermal Titration Calorimetry (ITC), Light Scattering, MicroScale Thermophoresis (MST), MicroScale Thermophoresis (M | 11/01/2022 |
RRID:SCR_022289 | Boston, MA 02115 | Computational - Interactive Compute/storage, Computational - High Performance Computing, High Performance Computing | 05/17/2022 |
RRID:SCR_022209 | Boston, MA 02115 | 3D Visualization, 3D & 4D Image Processing Stations, Cell Imaging, Clinical Imaging - Small Animal (luminescence/fluorescence), Confocal Microscopy, Confocal Microscope With FCS/FLIM Capabilities , Confocal/ Super Resolution Microscope, Consultation, Data Analysis And Interpretation, Data Processing, Data Visualization, Deconvolution, Fluorescence Lifetime, Fluorescence Microscope With Optical Sectioning Capability, Microscopy, Image Aquisition, Immunofluorescence , In-vivo Imaging, Live Cell Imaging, Multiphoton Microscopy, Multiphoton/ Harmonic Generation Microscope, Optical Imaging, Widefield Microscopy, Whole Slide Imaging, Training, TIRF Microscopy, Super-resolution Microscopy, Spatial Transcriptomics | 04/26/2022 |
RRID:SCR_007175 | Boston, MA 02115 | Central Laboratory Supply, Copy Number Variation (CNV), DNA Analysis, Genomics, Genotyping, Library Services, Molecular Library Services, Nucleic Acid Extraction, oligo synthesis, PCR Arrays, Real-time qPCR, RNA analysis, RNA Integrity, Sequencing - Capillary Sequencing, Sequencing - DNA Sequencing, Sequencing - Next Generation Sequencing (NGS), Shared Instrumentation Oversight & Maintenance | 09/15/2020 |
RRID:SCR_018822 | Boston, MA 02115 | Cell Imaging, Confocal Microscopy, Microscopy, Multiphoton Microscopy, Optical Imaging | 07/20/2020 |
Harvard Medical School
240 Longwood Ave.
Building C, room 303
Boston, MA 02115
United States of Americahttps://cmi.hms.harvard.educite this facility
Kelly Arnett
Last Updated: 11/01/2022
The Center for Macromolecular Interactions (CMI) in the department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School provides scientific consultation, training and access to shared biophysical equipment for the characterization and analysis of macromolecules and their complexes.
The facility offers training and access to instruments to measure molecular interactions by Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), MicroScale Thermophoresis (MST).
The facility also offers select data collection services, training and access on instruments to assess protein quality and biophysical properties by Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), Analytical Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS), Dynamic Light Scattering (DLS) and Mass Photometry (MP).
Using libraries developed in the lab of Andrew Kruse, the CMI is also offering yeast surface display nanobody selections services.
Services are offerred outside of Harvard Medical School
Consulting is offerred outside of Harvard Medical School