RRID:SCR_021857 | Lawrence, KS 66047 | Phosphoproteomics, HRAM Mass Spectrometry, Proteomics, Protocol Development, SDS-PAGE, Mass Spectrometry - Small Molecules, Mass Spectrometry - Proteins And Peptides, Nano-LC-MS -complex Mixtures, Thermal Protein Profiling - TPP, Global PTM Mapping, Label Free Quantitative Proteomics, Label Free Quantitative Prote | 01/31/2024 |
RRID:SCR_021801 | Lawrence, KS 66045 | 3D Visualization, Analysis Workstations, Processing & Embedding- Histology, H&E Staining, Bioimage Informatics, Image Processing And Analysis, Cell Imaging, Immuno Electron Microscopy, Immunohistochemistry, Immunohistochem | 07/06/2022 |
RRID:SCR_017749 | Lawrence, KS 66047 | Assays and Measurements, Biochemical Analysis, Cell Culture, Gel Chromatography, Molecular Construct Services, Nucleic Acid Extraction, Peptide Synthesis, Protein Extraction/Purification, SDS-PAGE, Spectroscopy, Surface Plasmon Resonance (SPR), Tissue Culture, Viral Vectors, Western Blot | 04/26/2022 |
RRID:SCR_021742 | Lawrence, KS 66047 | Single Crystal X-ray Pattern Analysis, X-Ray Crystallography, Structural Biology, Structure Determination | 10/05/2021 |
RRID:SCR_018671 | Lawrence, KS 66047 | 2D Spectra Acquisition and Interpretation, Data Analysis, Nuclear Magnetic Resonance (NMR), Spectroscopy | 01/07/2020 |
RRID:SCR_017752 | Lawrence, KS 66047 | Assays and Measurements, Biochemical Analysis, Cell Culture, Cell Imaging, Computational - Biostatistics, Confocal Microscopy, Data Analysis, Flow Cytometric Analysis, Surface Plasmon Resonance (SPR), Tissue Culture | 10/02/2019 |
RRID:SCR_017890 | Lawrence, KS 66047 | Computational - Application Development, Computational - Bioinformatics, Computational - High Performance Computing | 10/26/2016 |
RRID:SCR_017750 | Lawrence, KS 66047 | Molecular Library Services | 10/17/2011 |
University of Kansas, Lawrence
2034 Becker Drive
Delbert M. Shankel Structural Biology Center (SBC)
Lawrence, KS 66047
United States of Americahttp://medchem.cobre.ku.edu/cite this facility
Jeffrey Aube
Last Updated: 10/17/2011
The Synthetic Medicinal Chemistry Laboratory is a university-based drug discovery facility with a state-of-the-art infrastructure for pharmaceutical research. The Core provides medicinal, synthetic, and combinatorial chemistry support for Core B (HTS) and COBRE investigators. The support involves the optimization of compounds for potency, and selectivity by the following:
Preparing targeted libraries for screening and
lead optimization
Synthesizing organic compounds on various scales
(from mg to multi-gram)
Assisting COBRE investigators and other
university investigators, if requested, in the
design of novel ligands and in the development
of practical synthetic routes.
Services are offerred outside of University of Kansas, Lawrence